Targeting LSD1 suppresses stem cell-like properties and sensitizes head and neck squamous cell carcinoma to PD-1 blockade

Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive tumor with poor clinical outcomes due to recurrence, metastasis, and treatment resistance. Cancer stem cells (CSCs), a small population among tumor cells, are proposed to be responsible for tumor initiation, progression, metastasis...

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Detalles Bibliográficos
Autores principales: Han, Yong, Xu, Shengming, Ye, Weimin, Wang, Yang, Zhang, Xiangkai, Deng, Jiong, Zhang, Zhiyuan, Liu, Liu, Liu, Shuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542042/
https://www.ncbi.nlm.nih.gov/pubmed/34689153
http://dx.doi.org/10.1038/s41419-021-04297-0

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