Quantitative analysis of phosphoproteome in necroptosis reveals a role of TRIM28 phosphorylation in promoting necroptosis-induced cytokine production

Necroptosis is a form of regulated necrotic cell death that promotes inflammation. In cells undergoing necroptosis, activated RIPK1 kinase mediates the formation of RIPK1/RIPK3/MLKL complex to promote MLKL oligomerization and execution of necroptosis. RIPK1 kinase activity also promotes cell-autonom...

Descripción completa

Detalles Bibliográficos
Autores principales: Zu, Rui, Yu, Zhen, Zhao, Jing, Lu, Xiaojuan, Liang, Wei, Sun, Le, Si, Chenfang, Zhu, Kezhou, Zhang, Tian, Li, Ganquan, Zhang, Mengmeng, Zhang, Yaoyang, Liu, Nan, Yuan, Junying, Shan, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542044/
https://www.ncbi.nlm.nih.gov/pubmed/34689152
http://dx.doi.org/10.1038/s41419-021-04290-7

Ejemplares similares

Ejemplares similares