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USP15 Enhances the Proliferation, Migration, and Collagen Deposition of Hypertrophic Scar–Derived Fibroblasts by Deubiquitinating TGF-βR1 In Vitro

BACKGROUND: Hypertrophic scar is a fibroproliferative disorder caused by skin injury. The incidence of hypertrophic scar following trauma or burns is 40 to 70 percent or 70 percent, respectively. It has been shown that transforming growth factor (TGF) β1/Smad signaling plays a crucial role in hypert...

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Detalles Bibliográficos
Autores principales:	Tu, Longxiang, Lin, Zunwen, Huang, Qin, Liu, Dewu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Experimental
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542080/ https://www.ncbi.nlm.nih.gov/pubmed/34546211 http://dx.doi.org/10.1097/PRS.0000000000008488

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