Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome

BACKGROUND: Complex molecular programs in specific cell lineages govern human heart development. Hypoplastic left heart syndrome (HLHS) is the most common and severe manifestation within the spectrum of left ventricular outflow tract obstruction defects occurring in association with ventricular hypo...

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Detalles Bibliográficos
Autores principales: Krane, Markus, Dreßen, Martina, Santamaria, Gianluca, My, Ilaria, Schneider, Christine M., Dorn, Tatjana, Laue, Svenja, Mastantuono, Elisa, Berutti, Riccardo, Rawat, Hilansi, Gilsbach, Ralf, Schneider, Pedro, Lahm, Harald, Schwarz, Sascha, Doppler, Stefanie A., Paige, Sharon, Puluca, Nazan, Doll, Sophia, Neb, Irina, Brade, Thomas, Zhang, Zhong, Abou-Ajram, Claudia, Northoff, Bernd, Holdt, Lesca M., Sudhop, Stefanie, Sahara, Makoto, Goedel, Alexander, Dendorfer, Andreas, Tjong, Fleur V.Y., Rijlaarsdam, Maria E., Cleuziou, Julie, Lang, Nora, Kupatt, Christian, Bezzina, Connie, Lange, Rüdiger, Bowles, Neil E., Mann, Matthias, Gelb, Bruce D., Crotti, Lia, Hein, Lutz, Meitinger, Thomas, Wu, Sean, Sinnecker, Daniel, Gruber, Peter J., Laugwitz, Karl-Ludwig, Moretti, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542085/
https://www.ncbi.nlm.nih.gov/pubmed/34694888
http://dx.doi.org/10.1161/CIRCULATIONAHA.121.056198

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