Intravesical Condyloma Acuminata Progressing to Squamous Cell Carcinoma of the Bladder: An Unusual Presentation

Squamous cell carcinoma (SCC) of the bladder resulting from condyloma acuminata (CA) is uncommon. Most cases of SCC are asymptomatic until an advanced stage making the diagnosis difficult. Most patients present with urinary symptoms. We present the case of a 31-year-old African American male who presented to the emergency department with right lower extremity deep vein thrombosis. His past medical history was significant for recurrent bladder and urethral CA with high-grade dysplasia. A computed tomography (CT) gave the incidental findings of pelvic and bladder masses. The masses were studied and came back concerning for malignancy. The patient will undergo surgical removal soon. This manuscript illustrates an unusual presentation of CA progressing to SCC, including the diagnostic approach and treatment. We hope to increase awareness of the clinical presentation and regular follow-up in patients with risk factors.