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Postoperative continuous non-invasive cardiac output monitoring on the ward: a feasibility study
Postoperative hypotension is common (occurring in one third of patients) and is associated with worse clinical outcomes. The LiDCO CNAP (continuous non-invasive arterial pressure) device measures haemodynamics but has not been widely adopted in ward environments. Improved early detection of hypotens...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542541/ https://www.ncbi.nlm.nih.gov/pubmed/33094826 http://dx.doi.org/10.1007/s10877-020-00601-z |
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author | King, C. E. Kermode, A. Saxena, G. Carvelli, P. Edwards, M. Creagh-Brown, B. C. |
author_facet | King, C. E. Kermode, A. Saxena, G. Carvelli, P. Edwards, M. Creagh-Brown, B. C. |
author_sort | King, C. E. |
collection | PubMed |
description | Postoperative hypotension is common (occurring in one third of patients) and is associated with worse clinical outcomes. The LiDCO CNAP (continuous non-invasive arterial pressure) device measures haemodynamics but has not been widely adopted in ward environments. Improved early detection of hypotension by CNAP might guide interventions to improve clinical outcomes. We aimed to find the proportion of patients who tolerated LiDCO CNAP for 12 h postoperatively, to unmask episodes of hypotension detected by continuous monitoring and to characterise the haemodynamic profile at the time of hypotension. In this feasibility study, patients undergoing major elective surgery were continuously postoperatively monitored using CNAP. Haemodynamic data gathered from CNAP, including nSVRI (nominal systemic vascular resistance index), nSVI (nominal stroke volume index), SVV (stroke volume variation) and blood pressure, were analysed using Microsoft Excel and GraphPad Prism 8. 104 patients (age (mean ± sd): 68 ± 14, male (56%)) had CNAP sited postoperatively. 39% tolerated the CNAP device for at least 12 h. Within the 104 patients a mean of 81.2 min of hypotension detected by CNAP was not detected by usual care. The proportion of low/normal/high nSVI was 71%, 27% and 2%, nSVRI was 43%, 17% and 40%, respectively. CNAP monitoring was not tolerated for 12 h in the majority of patients. There were many episodes of hypotension unmasked through continuous monitoring. Based on the advanced haemodynamic data provided it is possible that the underlying cause of a third of postoperative hypotensive episodes is vasodilation rather than hypovolaemia. Trial registry number: NCT04010058 (ClinicalTrials.gov) Date of registration: 08/07/2019. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10877-020-00601-z) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-8542541 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-85425412021-11-08 Postoperative continuous non-invasive cardiac output monitoring on the ward: a feasibility study King, C. E. Kermode, A. Saxena, G. Carvelli, P. Edwards, M. Creagh-Brown, B. C. J Clin Monit Comput Original Research Postoperative hypotension is common (occurring in one third of patients) and is associated with worse clinical outcomes. The LiDCO CNAP (continuous non-invasive arterial pressure) device measures haemodynamics but has not been widely adopted in ward environments. Improved early detection of hypotension by CNAP might guide interventions to improve clinical outcomes. We aimed to find the proportion of patients who tolerated LiDCO CNAP for 12 h postoperatively, to unmask episodes of hypotension detected by continuous monitoring and to characterise the haemodynamic profile at the time of hypotension. In this feasibility study, patients undergoing major elective surgery were continuously postoperatively monitored using CNAP. Haemodynamic data gathered from CNAP, including nSVRI (nominal systemic vascular resistance index), nSVI (nominal stroke volume index), SVV (stroke volume variation) and blood pressure, were analysed using Microsoft Excel and GraphPad Prism 8. 104 patients (age (mean ± sd): 68 ± 14, male (56%)) had CNAP sited postoperatively. 39% tolerated the CNAP device for at least 12 h. Within the 104 patients a mean of 81.2 min of hypotension detected by CNAP was not detected by usual care. The proportion of low/normal/high nSVI was 71%, 27% and 2%, nSVRI was 43%, 17% and 40%, respectively. CNAP monitoring was not tolerated for 12 h in the majority of patients. There were many episodes of hypotension unmasked through continuous monitoring. Based on the advanced haemodynamic data provided it is possible that the underlying cause of a third of postoperative hypotensive episodes is vasodilation rather than hypovolaemia. Trial registry number: NCT04010058 (ClinicalTrials.gov) Date of registration: 08/07/2019. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10877-020-00601-z) contains supplementary material, which is available to authorized users. Springer Netherlands 2020-10-22 2021 /pmc/articles/PMC8542541/ /pubmed/33094826 http://dx.doi.org/10.1007/s10877-020-00601-z Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Research King, C. E. Kermode, A. Saxena, G. Carvelli, P. Edwards, M. Creagh-Brown, B. C. Postoperative continuous non-invasive cardiac output monitoring on the ward: a feasibility study |
title | Postoperative continuous non-invasive cardiac output monitoring on the ward: a feasibility study |
title_full | Postoperative continuous non-invasive cardiac output monitoring on the ward: a feasibility study |
title_fullStr | Postoperative continuous non-invasive cardiac output monitoring on the ward: a feasibility study |
title_full_unstemmed | Postoperative continuous non-invasive cardiac output monitoring on the ward: a feasibility study |
title_short | Postoperative continuous non-invasive cardiac output monitoring on the ward: a feasibility study |
title_sort | postoperative continuous non-invasive cardiac output monitoring on the ward: a feasibility study |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542541/ https://www.ncbi.nlm.nih.gov/pubmed/33094826 http://dx.doi.org/10.1007/s10877-020-00601-z |
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