Decreased production of epithelial-derived antimicrobial molecules at mucosal barriers during early life

Young age is a risk factor for respiratory and gastrointestinal infections. Here, we compared infant and adult mice to identify age-dependent mechanisms that drive susceptibility to mucosal infections during early life. Transcriptional profiling of the upper respiratory tract (URT) epithelium reveal...

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Detalles Bibliográficos
Autores principales: Lokken-Toyli, Kristen L., de Steenhuijsen Piters, Wouter A. A., Zangari, Tonia, Martel, Rachel, Kuipers, Kirsten, Shopsin, Bo, Loomis, Cynthia, Bogaert, Debby, Weiser, Jeffrey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542637/
https://www.ncbi.nlm.nih.gov/pubmed/34465896
http://dx.doi.org/10.1038/s41385-021-00438-y

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