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Early Pro-Inflammatory Signal and T-Cell Activation Associate With Vaccine-Induced Anti-Vaccinia Protective Neutralizing Antibodies

Both vaccine “take” and neutralizing antibody (nAb) titer are historical correlates for vaccine-induced protection from smallpox. We analyzed a subset of samples from a phase 2a trial of three DNA/HIV-1 primes and a recombinant Tiantan vaccinia virus-vectored (rTV)/HIV-1 booster and found that a pro...

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Detalles Bibliográficos
Autores principales:	Hou, Jue, Wang, Shuhui, Li, Dan, Carpp, Lindsay N., Zhang, Tong, Liu, Ying, Jia, Manxue, Peng, Hong, Liu, Chang, Wu, Hao, Huang, Yunda, Shao, Yiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542877/ https://www.ncbi.nlm.nih.gov/pubmed/34707608 http://dx.doi.org/10.3389/fimmu.2021.737487

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