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Non-Stimulatory pMHC Enhance CD8 T Cell Effector Functions by Recruiting Coreceptor-Bound Lck

Under physiological conditions, CD8(+) T cells need to recognize low numbers of antigenic pMHC class I complexes in the presence of a surplus of non-stimulatory, self pMHC class I on the surface of the APC. Non-stimulatory pMHC have been shown to enhance CD8(+) T cell responses to low amounts of ant...

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Detalles Bibliográficos
Autores principales:	Zhao, Xiang, Wu, Liang-Zhe, Ng, Esther K. Y., Leow, Kerisa W. S., Wei, Qianru, Gascoigne, Nicholas R. J., Brzostek, Joanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542885/ https://www.ncbi.nlm.nih.gov/pubmed/34707605 http://dx.doi.org/10.3389/fimmu.2021.721722

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