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Exome-Wide Association Study Identifies East Asian-Specific Missense Variant MTHFR C136T Influencing Homocysteine Levels in Chinese Populations RH: ExWAS of tHCY in a Chinese Population

Plasma total homocysteine (tHCY) is a known risk factor of a wide range of complex diseases. No genome scans for tHCY have been conducted in East Asian populations. Here, we conducted an exome-wide association study (ExWAS) for tHCY in 5,175 individuals of Chinese Han origin, followed by a replicati...

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Detalles Bibliográficos
Autores principales:	Liu, Tianzi, Momin, Mohetaboer, Zhou, Huiyue, Zheng, Qiwen, Fan, Fangfang, Jia, Jia, Liu, Mengyuan, Bao, Minghui, Li, Jianping, Huo, Yong, Liu, Jialin, Zhang, Yaning, Mao, Xuemei, Han, Xiao, Hu, Zhiyuan, Zeng, Changqing, Liu, Fan, Zhang, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542906/ https://www.ncbi.nlm.nih.gov/pubmed/34707639 http://dx.doi.org/10.3389/fgene.2021.717621

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