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p38 MAP Kinase Signaling in Microglia Plays a Sex-Specific Protective Role in CNS Autoimmunity and Regulates Microglial Transcriptional States
Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system, representing the leading cause of non-traumatic neurologic disease in young adults. This disease is three times more common in women, yet more severe in men, but the mechanisms underlying these sex differen...
Autores principales: | McGill, Mahalia M., Richman, Alyssa R., Boyd, Joseph R., Sabikunnahar, Bristy, Lahue, Karolyn G., Montgomery, Theresa L., Caldwell, Sydney, Varnum, Stella, Frietze, Seth, Krementsov, Dimitry N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542909/ https://www.ncbi.nlm.nih.gov/pubmed/34707603 http://dx.doi.org/10.3389/fimmu.2021.715311 |
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