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Integrated Metagenomics and Metabolomics to Reveal the Effects of Policosanol on Modulating the Gut Microbiota and Lipid Metabolism in Hyperlipidemic C57BL/6 Mice

The aim of the study was to investigate the regulatory effects of policosanol on hyperlipidemia, gut microbiota and metabolic status in a C57BL/6 mouse model. A total of 35 C57BL/6 mice were assigned to 3 groups, chow (n=12), high fat diet (HFD, n=12) and HFD+policosanol (n=11), then treated for 18...

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Detalles Bibliográficos
Autores principales: Zhai, Zhenya, Liu, Jianping, Niu, Kai-Min, Lin, Chong, Tu, Yue, Liu, Yichun, Cai, Lichuang, Liu, Huiping, Ouyang, Kexian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542985/
https://www.ncbi.nlm.nih.gov/pubmed/34707567
http://dx.doi.org/10.3389/fendo.2021.722055