Rapid Identification of the Tumor-Specific Reactive TIL Repertoire via Combined Detection of CD137, TNF, and IFNγ, Following Recognition of Autologous Tumor-Antigens

Detecting the entire repertoire of tumor-specific reactive tumor-infiltrating lymphocytes (TILs) is essential for investigating their immunological functions in the tumor microenvironment. Current in vitro assays identifying tumor-specific functional activation measure the upregulation of surface mo...

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Detalles Bibliográficos
Autores principales: Draghi, Arianna, Chamberlain, Christopher Aled, Khan, Shawez, Papp, Krisztian, Lauss, Martin, Soraggi, Samuele, Radic, Haja Dominike, Presti, Mario, Harbst, Katja, Gokuldass, Aishwarya, Kverneland, Anders, Nielsen, Morten, Westergaard, Marie Christine Wulff, Andersen, Mads Hald, Csabai, Istvan, Jönsson, Göran, Szallasi, Zoltan, Svane, Inge Marie, Donia, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543011/
https://www.ncbi.nlm.nih.gov/pubmed/34707600
http://dx.doi.org/10.3389/fimmu.2021.705422

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