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Pharmacological MRI with Simultaneous Measurement of Cerebral Perfusion and Blood-Cerebrospinal Fluid Barrier Function using Interleaved Echo-Time Arterial Spin Labelling
Pharmacological MRI (phMRI) studies seek to capture changes in brain haemodynamics in response to a drug. This provides a methodological platform for the evaluation of novel therapeutics, and when applied to disease states, may provide diagnostic or mechanistic information pertaining to common brain...
Autores principales: | Perera, Charith, Harrison, Ian F., Lythgoe, Mark F., Thomas, David L., Wells, Jack A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543042/ https://www.ncbi.nlm.nih.gov/pubmed/34144160 http://dx.doi.org/10.1016/j.neuroimage.2021.118270 |
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