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Development and characterization of an animal model of Japanese encephalitis virus infection in adolescent C57BL/6 mouse

A mouse-adapted isolate of Japanese encephalitis virus (JEV), designated as JEV-S3, was generated by serially passaging the P20778 strain of the virus in 3- to 4-week-old C57BL/6 mice. Blood-brain barrier leakage was evident in JEV-S3-infected mice, in which viral antigens and RNA were consistently...

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Detalles Bibliográficos
Autores principales: Tripathi, Aarti, Banerjee, Arup, Vrati, Sudhanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543065/
https://www.ncbi.nlm.nih.gov/pubmed/34447981
http://dx.doi.org/10.1242/dmm.049176