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Effect of zinc oxide nanoparticles on physical and antimicrobial properties of resin-modified glass ionomer cement
BACKGROUND: To improve the limitations, many modifications in the resin-modified glass ionomer (RMGI) composition have been proposed. In this study, we evaluated the effect of different concentrations of zinc oxide (ZnO) nanoparticles incorporated into RMGI cement on its physical and antimicrobial p...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543101/ https://www.ncbi.nlm.nih.gov/pubmed/34760064 http://dx.doi.org/10.4103/1735-3327.326646 |
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author | Malekhoseini, Zahra Rezvani, Mohammad Bagher Niakan, Mohammad Atai, Mohammad Bassir, Mahshid Mohammadi Alizade, Hamid Safar Siabani, Saba |
author_facet | Malekhoseini, Zahra Rezvani, Mohammad Bagher Niakan, Mohammad Atai, Mohammad Bassir, Mahshid Mohammadi Alizade, Hamid Safar Siabani, Saba |
author_sort | Malekhoseini, Zahra |
collection | PubMed |
description | BACKGROUND: To improve the limitations, many modifications in the resin-modified glass ionomer (RMGI) composition have been proposed. In this study, we evaluated the effect of different concentrations of zinc oxide (ZnO) nanoparticles incorporated into RMGI cement on its physical and antimicrobial properties. MATERIALS AND METHODS: In this in vitro study, ZnO nanoparticles with 0–4 wt.% concentrations were incorporated into RMGI. The following tests were carried out: (a) Antibacterial activity against Streptococcus mutans tested by disc diffusion method, (b) mechanical behavior assessment by measuring flexural strength (FS) and flexural modulus (FM), (c) micro-shear bond strength (μ-SBS), and (d) fluoride and zinc release. Data were analyzed using the statistical tests of ANOVA, t-test, and Tukey's HSD post hoc in SPSS V22. The level of significancy was 0.05. RESULTS: In the disc diffusion method, specimens with 2 wt.% ZnO nanoparticles showed the highest antimicrobial efficacy (P < 0.05). After 1 month of water storage, no significant difference was observed in FS and FM of the samples (P > 0.05). In 2 wt.% ZnO nanoparticles group, μSBS increased in the first 7 days but decreased by 17% after one month, which showed a significant difference with that of the control group. The fluoride release did no change in the ZnO nanoparticle-containing group compared with the control group at all time intervals. CONCLUSION: Incorporation of 2 wt.% ZnO nanoparticles into the RMGI cement adds antimicrobial activity to the cement without sacrificing FS and fluoride release properties, while decreased μSBS. |
format | Online Article Text |
id | pubmed-8543101 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-85431012021-11-09 Effect of zinc oxide nanoparticles on physical and antimicrobial properties of resin-modified glass ionomer cement Malekhoseini, Zahra Rezvani, Mohammad Bagher Niakan, Mohammad Atai, Mohammad Bassir, Mahshid Mohammadi Alizade, Hamid Safar Siabani, Saba Dent Res J (Isfahan) Original Article BACKGROUND: To improve the limitations, many modifications in the resin-modified glass ionomer (RMGI) composition have been proposed. In this study, we evaluated the effect of different concentrations of zinc oxide (ZnO) nanoparticles incorporated into RMGI cement on its physical and antimicrobial properties. MATERIALS AND METHODS: In this in vitro study, ZnO nanoparticles with 0–4 wt.% concentrations were incorporated into RMGI. The following tests were carried out: (a) Antibacterial activity against Streptococcus mutans tested by disc diffusion method, (b) mechanical behavior assessment by measuring flexural strength (FS) and flexural modulus (FM), (c) micro-shear bond strength (μ-SBS), and (d) fluoride and zinc release. Data were analyzed using the statistical tests of ANOVA, t-test, and Tukey's HSD post hoc in SPSS V22. The level of significancy was 0.05. RESULTS: In the disc diffusion method, specimens with 2 wt.% ZnO nanoparticles showed the highest antimicrobial efficacy (P < 0.05). After 1 month of water storage, no significant difference was observed in FS and FM of the samples (P > 0.05). In 2 wt.% ZnO nanoparticles group, μSBS increased in the first 7 days but decreased by 17% after one month, which showed a significant difference with that of the control group. The fluoride release did no change in the ZnO nanoparticle-containing group compared with the control group at all time intervals. CONCLUSION: Incorporation of 2 wt.% ZnO nanoparticles into the RMGI cement adds antimicrobial activity to the cement without sacrificing FS and fluoride release properties, while decreased μSBS. Wolters Kluwer - Medknow 2021-09-25 /pmc/articles/PMC8543101/ /pubmed/34760064 http://dx.doi.org/10.4103/1735-3327.326646 Text en Copyright: © 2021 Dental Research Journal https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Malekhoseini, Zahra Rezvani, Mohammad Bagher Niakan, Mohammad Atai, Mohammad Bassir, Mahshid Mohammadi Alizade, Hamid Safar Siabani, Saba Effect of zinc oxide nanoparticles on physical and antimicrobial properties of resin-modified glass ionomer cement |
title | Effect of zinc oxide nanoparticles on physical and antimicrobial properties of resin-modified glass ionomer cement |
title_full | Effect of zinc oxide nanoparticles on physical and antimicrobial properties of resin-modified glass ionomer cement |
title_fullStr | Effect of zinc oxide nanoparticles on physical and antimicrobial properties of resin-modified glass ionomer cement |
title_full_unstemmed | Effect of zinc oxide nanoparticles on physical and antimicrobial properties of resin-modified glass ionomer cement |
title_short | Effect of zinc oxide nanoparticles on physical and antimicrobial properties of resin-modified glass ionomer cement |
title_sort | effect of zinc oxide nanoparticles on physical and antimicrobial properties of resin-modified glass ionomer cement |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543101/ https://www.ncbi.nlm.nih.gov/pubmed/34760064 http://dx.doi.org/10.4103/1735-3327.326646 |
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