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Visual hallucinations and sight loss in children and young adults: a retrospective case series of Charles Bonnet syndrome
BACKGROUND/AIMS: Charles Bonnet syndrome (CBS) is a complication of sight loss affecting all ages; yet, few childhood cases have been reported. Our aim is to raise awareness of this under-reported association occurring in children and young adults in order to prevent psychological harm in this age g...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543192/ https://www.ncbi.nlm.nih.gov/pubmed/32933935 http://dx.doi.org/10.1136/bjophthalmol-2020-317237 |
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author | Jones, Lee Moosajee, Mariya |
author_facet | Jones, Lee Moosajee, Mariya |
author_sort | Jones, Lee |
collection | PubMed |
description | BACKGROUND/AIMS: Charles Bonnet syndrome (CBS) is a complication of sight loss affecting all ages; yet, few childhood cases have been reported. Our aim is to raise awareness of this under-reported association occurring in children and young adults in order to prevent psychological harm in this age group. METHODS: A retrospective case series reviewing medical notes of patients <25 years of age with sight loss and reported CBS at a single centre hospital eye service in London, United Kingdom. Search of electronic patient records identified 13 patients experiencing hallucinatory events over a 9-year period. Outcomes were patient demographics including ocular diagnosis, visual acuity at time of onset, characteristics of hallucinations, clinical management strategies and patient-reported affliction. RESULTS: Eight patients were diagnosed with progressive inherited retinal diseases, primarily Stargardt disease (N=5). Clinical history indicated patients had significantly reduced best-corrected visual acuity (BCVA) in at least one eye at onset; median (IQR) worse eye BCVA was 1.0 (0.86–1.6) logarithm of minimum angle of resolution(LogMAR). CBS significantly affected patients’ personal lives including education, diet and sleep. Clinical management was varied, mostly relating to reassurance at the point of contact. CONCLUSION: We describe the clinical features of young patients with CBS, with management strategies and aspects of negative outcomes. High potential caseload and risk of psychological harm merit further research. Increased awareness among healthcare professionals and patient education to forewarn susceptible individuals may reduce the overall impact and improve coping with symptoms. |
format | Online Article Text |
id | pubmed-8543192 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-85431922021-11-10 Visual hallucinations and sight loss in children and young adults: a retrospective case series of Charles Bonnet syndrome Jones, Lee Moosajee, Mariya Br J Ophthalmol Clinical Science BACKGROUND/AIMS: Charles Bonnet syndrome (CBS) is a complication of sight loss affecting all ages; yet, few childhood cases have been reported. Our aim is to raise awareness of this under-reported association occurring in children and young adults in order to prevent psychological harm in this age group. METHODS: A retrospective case series reviewing medical notes of patients <25 years of age with sight loss and reported CBS at a single centre hospital eye service in London, United Kingdom. Search of electronic patient records identified 13 patients experiencing hallucinatory events over a 9-year period. Outcomes were patient demographics including ocular diagnosis, visual acuity at time of onset, characteristics of hallucinations, clinical management strategies and patient-reported affliction. RESULTS: Eight patients were diagnosed with progressive inherited retinal diseases, primarily Stargardt disease (N=5). Clinical history indicated patients had significantly reduced best-corrected visual acuity (BCVA) in at least one eye at onset; median (IQR) worse eye BCVA was 1.0 (0.86–1.6) logarithm of minimum angle of resolution(LogMAR). CBS significantly affected patients’ personal lives including education, diet and sleep. Clinical management was varied, mostly relating to reassurance at the point of contact. CONCLUSION: We describe the clinical features of young patients with CBS, with management strategies and aspects of negative outcomes. High potential caseload and risk of psychological harm merit further research. Increased awareness among healthcare professionals and patient education to forewarn susceptible individuals may reduce the overall impact and improve coping with symptoms. BMJ Publishing Group 2021-11 2020-09-15 /pmc/articles/PMC8543192/ /pubmed/32933935 http://dx.doi.org/10.1136/bjophthalmol-2020-317237 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Clinical Science Jones, Lee Moosajee, Mariya Visual hallucinations and sight loss in children and young adults: a retrospective case series of Charles Bonnet syndrome |
title | Visual hallucinations and sight loss in children and young adults: a retrospective case series of Charles Bonnet syndrome |
title_full | Visual hallucinations and sight loss in children and young adults: a retrospective case series of Charles Bonnet syndrome |
title_fullStr | Visual hallucinations and sight loss in children and young adults: a retrospective case series of Charles Bonnet syndrome |
title_full_unstemmed | Visual hallucinations and sight loss in children and young adults: a retrospective case series of Charles Bonnet syndrome |
title_short | Visual hallucinations and sight loss in children and young adults: a retrospective case series of Charles Bonnet syndrome |
title_sort | visual hallucinations and sight loss in children and young adults: a retrospective case series of charles bonnet syndrome |
topic | Clinical Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543192/ https://www.ncbi.nlm.nih.gov/pubmed/32933935 http://dx.doi.org/10.1136/bjophthalmol-2020-317237 |
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