Simvastatin Treatment Does Not Ameliorate Muscle Pathophysiology in a Mouse Model for Duchenne Muscular Dystrophy

Duchenne muscular dystrophy is an X-linked, recessive muscular dystrophy in which the absence of the dystrophin protein leads to fibrosis, inflammation and oxidative stress, resulting in loss of muscle tissue. Drug repurposing, i.e. using drugs already approved for other disorders, is attractive as...

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Detalles Bibliográficos
Autores principales: Verhaart, Ingrid E.C., Cappellari, Ornella, Tanganyika-de Winter, Christa L., Plomp, Jaap J., Nnorom, Sofia, Wells, Kim E., Hildyard, John C.W., Bull, David, Aartsma-Rus, Annemieke, Wells, Dominic J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2021
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543260/
https://www.ncbi.nlm.nih.gov/pubmed/33044191
http://dx.doi.org/10.3233/JND-200524

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