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Gene Therapy to Modulate Alpha-Synuclein in Synucleinopathies

The protein alpha-Synuclein (α-Syn) is a key contributor to the etiology of Parkinson’s disease (PD) with aggregation, trans-neuronal spread, and/or depletion of α-Syn being viewed as crucial events in the molecular processes that result in neurodegeneration. The exact succession of pathological occ...

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Detalles Bibliográficos
Autores principales:	Sandoval, Ivette M., Marmion, David J., Meyers, Kimberly T., Manfredsson, Fredric P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543271/ https://www.ncbi.nlm.nih.gov/pubmed/34092656 http://dx.doi.org/10.3233/JPD-212679

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