USP10 Promotes Fibronectin Recycling, Secretion, and Organization

PURPOSE: Integrins play a central role in myofibroblast pathological adhesion, over-contraction, and TGFβ activation. Previously, we demonstrated that after corneal wounding, αv integrins are protected from intracellular degradation by upregulation of the deubiquitinase USP10, leading to cell-surfac...

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Detalles Bibliográficos
Autores principales: Phillips, Andrew T., Boumil, Edward F., Castro, Nileyma, Venkatesan, Arunkumar, Gallo, Eugenio, Adams, Jarrett J., Sidhu, Sachdev S., Bernstein, Audrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543399/
https://www.ncbi.nlm.nih.gov/pubmed/34665194
http://dx.doi.org/10.1167/iovs.62.13.15

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