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Intranasal delivery of replicating mRNA encoding neutralizing antibody against SARS-CoV-2 infection in mice

The lung is the prophylaxis target against SARS-CoV-2 infection, and neutralizing antibodies are a leading class of biological products against various infectious viral pathogen. In this study, we develop a safe and cost-effective platform to express neutralizing antibody in the lung with replicatin...

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Detalles Bibliográficos
Autores principales:	Li, Jia-Qi, Zhang, Zhe-Rui, Zhang, Hong-Qing, Zhang, Ya-Nan, Zeng, Xiang-Yue, Zhang, Qiu-Yan, Deng, Cheng-Lin, Li, Xiao-Dan, Zhang, Bo, Ye, Han-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543430/ https://www.ncbi.nlm.nih.gov/pubmed/34697295 http://dx.doi.org/10.1038/s41392-021-00783-1

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