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Exercise alone impacts short-term adult visual neuroplasticity in a monocular deprivation paradigm

Adult homeostatic visual plasticity can be induced by short-term patching, heralded by a shift in ocular dominance in favor of the deprived eye after monocular occlusion. The potential to boost visual neuroplasticity with environmental enrichment such as exercise has also been explored; however, the...

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Autores principales: Virathone, Lucas, Nguyen, Bao N., Dobson, Fiona, Carter, Olivia L., McKendrick, Allison M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543434/
https://www.ncbi.nlm.nih.gov/pubmed/34668930
http://dx.doi.org/10.1167/jov.21.11.12
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author Virathone, Lucas
Nguyen, Bao N.
Dobson, Fiona
Carter, Olivia L.
McKendrick, Allison M.
author_facet Virathone, Lucas
Nguyen, Bao N.
Dobson, Fiona
Carter, Olivia L.
McKendrick, Allison M.
author_sort Virathone, Lucas
collection PubMed
description Adult homeostatic visual plasticity can be induced by short-term patching, heralded by a shift in ocular dominance in favor of the deprived eye after monocular occlusion. The potential to boost visual neuroplasticity with environmental enrichment such as exercise has also been explored; however, the results are inconsistent, with some studies finding no additive effect of exercise. Studies to date have only considered the effect of patching alone or in combination with exercise. Whether exercise alone affects typical outcome measures of experimental estimates of short-term visual neuroplasticity is unknown. We therefore measured binocular rivalry in 20 healthy young adults (20–34 years old) at baseline and after three 2-hour interventions: patching (of the dominant eye) only, patching with exercise, and exercise only. Consistent with previous work, the patching interventions produced a shift in ocular dominance toward the deprived (dominant) eye. Mild- to moderate-intensity exercise in the absence of patching had several effects on binocular rivalry metrics, including a reduction in the dominant eye percept. The proportion of mixed percept and the time to first switch (onset rivalry) did not change from baseline across all interventions. Thus, we demonstrate that exercise alone can impact binocular rivalry outcomes measures. We did not observe a synergistic effect between patching and exercise in our data.
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spelling pubmed-85434342021-10-29 Exercise alone impacts short-term adult visual neuroplasticity in a monocular deprivation paradigm Virathone, Lucas Nguyen, Bao N. Dobson, Fiona Carter, Olivia L. McKendrick, Allison M. J Vis Article Adult homeostatic visual plasticity can be induced by short-term patching, heralded by a shift in ocular dominance in favor of the deprived eye after monocular occlusion. The potential to boost visual neuroplasticity with environmental enrichment such as exercise has also been explored; however, the results are inconsistent, with some studies finding no additive effect of exercise. Studies to date have only considered the effect of patching alone or in combination with exercise. Whether exercise alone affects typical outcome measures of experimental estimates of short-term visual neuroplasticity is unknown. We therefore measured binocular rivalry in 20 healthy young adults (20–34 years old) at baseline and after three 2-hour interventions: patching (of the dominant eye) only, patching with exercise, and exercise only. Consistent with previous work, the patching interventions produced a shift in ocular dominance toward the deprived (dominant) eye. Mild- to moderate-intensity exercise in the absence of patching had several effects on binocular rivalry metrics, including a reduction in the dominant eye percept. The proportion of mixed percept and the time to first switch (onset rivalry) did not change from baseline across all interventions. Thus, we demonstrate that exercise alone can impact binocular rivalry outcomes measures. We did not observe a synergistic effect between patching and exercise in our data. The Association for Research in Vision and Ophthalmology 2021-10-20 /pmc/articles/PMC8543434/ /pubmed/34668930 http://dx.doi.org/10.1167/jov.21.11.12 Text en Copyright 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
spellingShingle Article
Virathone, Lucas
Nguyen, Bao N.
Dobson, Fiona
Carter, Olivia L.
McKendrick, Allison M.
Exercise alone impacts short-term adult visual neuroplasticity in a monocular deprivation paradigm
title Exercise alone impacts short-term adult visual neuroplasticity in a monocular deprivation paradigm
title_full Exercise alone impacts short-term adult visual neuroplasticity in a monocular deprivation paradigm
title_fullStr Exercise alone impacts short-term adult visual neuroplasticity in a monocular deprivation paradigm
title_full_unstemmed Exercise alone impacts short-term adult visual neuroplasticity in a monocular deprivation paradigm
title_short Exercise alone impacts short-term adult visual neuroplasticity in a monocular deprivation paradigm
title_sort exercise alone impacts short-term adult visual neuroplasticity in a monocular deprivation paradigm
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543434/
https://www.ncbi.nlm.nih.gov/pubmed/34668930
http://dx.doi.org/10.1167/jov.21.11.12
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