The effect of opioids on gastrointestinal function in the ICU

Gastrointestinal (GI) dysfunction is common in the critical care setting and is highly associated with clinical outcomes. Opioids increase the risk for GI dysfunction and are frequently prescribed to reduce pain in critically ill patients. However, the role of opioids in GI function remains uncertai...

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Autores principales: Yan, Yun, Chen, Yu, Zhang, Xijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543814/
https://www.ncbi.nlm.nih.gov/pubmed/34689805
http://dx.doi.org/10.1186/s13054-021-03793-1
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author Yan, Yun
Chen, Yu
Zhang, Xijing
author_facet Yan, Yun
Chen, Yu
Zhang, Xijing
author_sort Yan, Yun
collection PubMed
description Gastrointestinal (GI) dysfunction is common in the critical care setting and is highly associated with clinical outcomes. Opioids increase the risk for GI dysfunction and are frequently prescribed to reduce pain in critically ill patients. However, the role of opioids in GI function remains uncertain in the ICU. This review aims to describe the effect of opioids on GI motility, their potential risk of increasing infection and the treatment of GI dysmotility with opioid antagonists in the ICU setting.
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spelling pubmed-85438142021-10-25 The effect of opioids on gastrointestinal function in the ICU Yan, Yun Chen, Yu Zhang, Xijing Crit Care Review Gastrointestinal (GI) dysfunction is common in the critical care setting and is highly associated with clinical outcomes. Opioids increase the risk for GI dysfunction and are frequently prescribed to reduce pain in critically ill patients. However, the role of opioids in GI function remains uncertain in the ICU. This review aims to describe the effect of opioids on GI motility, their potential risk of increasing infection and the treatment of GI dysmotility with opioid antagonists in the ICU setting. BioMed Central 2021-10-24 /pmc/articles/PMC8543814/ /pubmed/34689805 http://dx.doi.org/10.1186/s13054-021-03793-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Yan, Yun
Chen, Yu
Zhang, Xijing
The effect of opioids on gastrointestinal function in the ICU
title The effect of opioids on gastrointestinal function in the ICU
title_full The effect of opioids on gastrointestinal function in the ICU
title_fullStr The effect of opioids on gastrointestinal function in the ICU
title_full_unstemmed The effect of opioids on gastrointestinal function in the ICU
title_short The effect of opioids on gastrointestinal function in the ICU
title_sort effect of opioids on gastrointestinal function in the icu
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543814/
https://www.ncbi.nlm.nih.gov/pubmed/34689805
http://dx.doi.org/10.1186/s13054-021-03793-1
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