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The structure of blood–tumor barrier and distribution of chemotherapeutic drugs in non-small cell lung cancer brain metastases

BACKGROUND: Brain metastasis is an important cause of increased mortality in patients with non-small cell lung cancer (NSCLC). In brain metastasis, the blood–brain barrier (BBB) is frequently impaired, forming blood–tumor barrier (BTB). The efficacy of chemotherapy is usually very poor. However, the...

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Detalles Bibliográficos
Autores principales: Ye, Ling-yun, Sun, Li-xiang, Zhong, Xiu-hua, Chen, Xue-song, Hu, Song, Xu, Rong-rong, Zeng, Xiao-ning, Xie, Wei-ping, Kong, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543815/
https://www.ncbi.nlm.nih.gov/pubmed/34689774
http://dx.doi.org/10.1186/s12935-021-02263-6