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Activation of the EGFR-PI3K-CaM pathway by PRL-1-overexpressing placenta-derived mesenchymal stem cells ameliorates liver cirrhosis via ER stress-dependent calcium

BACKGROUND: Cholesterol accumulation and calcium depletion induce hepatic injury via the endoplasmic reticulum (ER) stress response. ER stress regulates the calcium imbalance between the ER and mitochondria. We previously reported that phosphatase of regenerating liver-1 (PRL-1)-overexpressing place...

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Detalles Bibliográficos
Autores principales:	Kim, Se Ho, Kim, Jae Yeon, Park, Soo Young, Jeong, Won Tae, Kim, Jin Man, Bae, Si Hyun, Kim, Gi Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8543968/ https://www.ncbi.nlm.nih.gov/pubmed/34689832 http://dx.doi.org/10.1186/s13287-021-02616-y

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