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Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology

PURPOSE: Alcohol delamination of the corneal epithelium (ADCE) is a therapeutic option for patients with recurrent corneal erosion (RCE) who do not respond to nonsurgical management of lubricants and extended wear contact lens. The aim of the study is to report on three-year efficacy and safety of A...

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Autores principales: Teh, Boon Lin, Chua, Paul Y S, Reddy, Aravind R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544076/
https://www.ncbi.nlm.nih.gov/pubmed/34427239
http://dx.doi.org/10.4103/ijo.IJO_3796_20
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author Teh, Boon Lin
Chua, Paul Y S
Reddy, Aravind R
author_facet Teh, Boon Lin
Chua, Paul Y S
Reddy, Aravind R
author_sort Teh, Boon Lin
collection PubMed
description PURPOSE: Alcohol delamination of the corneal epithelium (ADCE) is a therapeutic option for patients with recurrent corneal erosion (RCE) who do not respond to nonsurgical management of lubricants and extended wear contact lens. The aim of the study is to report on three-year efficacy and safety of ADCE for RCE of traumatic etiology. METHODS: This is a retrospective review of consecutive patients who underwent ADCE for traumatic RCE in a local hospital between January 2010 and January 2020. The outcomes at a 3-year follow-up review are included. Nonsurgical therapy used; intra- and postoperative complications were recorded. ADCE was only offered to those who remained symptomatic despite maximum topical lubrications and/or extended wear contact lens. Success was defined as the absence of recurrence of corneal erosion. RESULTS: Twenty-six eyes of 26 patients with RCE caused by trauma underwent ADCE. The mean age of patients was 39 years. The follow-up period was a minimum of 36 months. Three eyes (11.5%) had recurrence of corneal erosion after ADCE at the 3-year follow-up. Recurrence was noted at months 2, 23, and 36 postoperatively in these patients. All patients reported significant improvement in symptoms associated with recurrent erosion. Ten eyes (38.5%) stopped all topical lubricants postoperatively. No intra- or postoperative complications were noted in our study. CONCLUSION: This study documents the long-term safety and efficacy of alcohol delamination of corneal epithelium at 3 years for patients with RCE of traumatic origin.
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spelling pubmed-85440762021-10-29 Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology Teh, Boon Lin Chua, Paul Y S Reddy, Aravind R Indian J Ophthalmol Special Focus, Ocular Surface and Cornea, Original Article PURPOSE: Alcohol delamination of the corneal epithelium (ADCE) is a therapeutic option for patients with recurrent corneal erosion (RCE) who do not respond to nonsurgical management of lubricants and extended wear contact lens. The aim of the study is to report on three-year efficacy and safety of ADCE for RCE of traumatic etiology. METHODS: This is a retrospective review of consecutive patients who underwent ADCE for traumatic RCE in a local hospital between January 2010 and January 2020. The outcomes at a 3-year follow-up review are included. Nonsurgical therapy used; intra- and postoperative complications were recorded. ADCE was only offered to those who remained symptomatic despite maximum topical lubrications and/or extended wear contact lens. Success was defined as the absence of recurrence of corneal erosion. RESULTS: Twenty-six eyes of 26 patients with RCE caused by trauma underwent ADCE. The mean age of patients was 39 years. The follow-up period was a minimum of 36 months. Three eyes (11.5%) had recurrence of corneal erosion after ADCE at the 3-year follow-up. Recurrence was noted at months 2, 23, and 36 postoperatively in these patients. All patients reported significant improvement in symptoms associated with recurrent erosion. Ten eyes (38.5%) stopped all topical lubricants postoperatively. No intra- or postoperative complications were noted in our study. CONCLUSION: This study documents the long-term safety and efficacy of alcohol delamination of corneal epithelium at 3 years for patients with RCE of traumatic origin. Wolters Kluwer - Medknow 2021-09 2021-08-25 /pmc/articles/PMC8544076/ /pubmed/34427239 http://dx.doi.org/10.4103/ijo.IJO_3796_20 Text en Copyright: © 2021 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Special Focus, Ocular Surface and Cornea, Original Article
Teh, Boon Lin
Chua, Paul Y S
Reddy, Aravind R
Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
title Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
title_full Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
title_fullStr Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
title_full_unstemmed Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
title_short Three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
title_sort three-year outcomes of alcohol delamination of corneal epithelium for recurrent corneal erosions of traumatic etiology
topic Special Focus, Ocular Surface and Cornea, Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544076/
https://www.ncbi.nlm.nih.gov/pubmed/34427239
http://dx.doi.org/10.4103/ijo.IJO_3796_20
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