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Screening and Identification of a Novel Anti-tuberculosis Compound That Targets Deoxyuridine 5′-Triphosphate Nucleotidohydrolase

Tuberculosis (TB) is still a threat to humans worldwide. The rise of drug-resistant TB strains has escalated the need for developing effective anti-TB agents. Deoxyuridine 5′-triphosphate nucleotidohydrolase (dUTPase) is essential for thymidylate biosynthesis to maintain the DNA integrity. In Mycoba...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Zhang, Hongjuan, Chen, Ying, Qiao, Luyao, Han, Yanxing, Lin, Yuan, Si, Shuyi, Jiang, Jian-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544286/
https://www.ncbi.nlm.nih.gov/pubmed/34707597
http://dx.doi.org/10.3389/fmicb.2021.757914