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lncRNA MEG3 aggravated neuropathic pain and astrocyte overaction through mediating miR-130a-5p/CXCL12/CXCR4 axis

Objective: Long non-coding RNAs (lncRNAs) exert a critical function in mediating neuropathic pain (NP). MEG3, a novel lncRNA, contributes to astrocyte activation and inflammation. However, its role in NP remains unclear. Methods: The chronic constriction injury (CCI) method was employed to construct...

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Detalles Bibliográficos
Autores principales: Dong, Jiacai, Xia, Rui, Zhang, Zhonggui, Xu, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544300/
https://www.ncbi.nlm.nih.gov/pubmed/34609952
http://dx.doi.org/10.18632/aging.203592