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A Rare Case of Posterior Fossa Tumor and Central Precocious Puberty: Case Presentation and Review of the Literature
Central precocious puberty (CPP) is a condition that causes early gonadotropin-dependent sexual development; CPP is idiopathic in girls in most cases, whereas more than 50% of boys have an identifiable etiology. We conducted a qualitative systematic review following the ENTREQ (enhancing transparenc...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544465/ https://www.ncbi.nlm.nih.gov/pubmed/34698255 http://dx.doi.org/10.3390/neurolint13040053 |
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author | Rana, Roberta Perrillo, Teresa Santoro, Nicola Ortolani, Federica Messina, Raffaella Resta, Mariachiara Perrucci, Ilenia Ingravallo, Giuseppe Cazzato, Gerardo Grassi, Massimo Pesce, Sabino Signorelli, Francesco |
author_facet | Rana, Roberta Perrillo, Teresa Santoro, Nicola Ortolani, Federica Messina, Raffaella Resta, Mariachiara Perrucci, Ilenia Ingravallo, Giuseppe Cazzato, Gerardo Grassi, Massimo Pesce, Sabino Signorelli, Francesco |
author_sort | Rana, Roberta |
collection | PubMed |
description | Central precocious puberty (CPP) is a condition that causes early gonadotropin-dependent sexual development; CPP is idiopathic in girls in most cases, whereas more than 50% of boys have an identifiable etiology. We conducted a qualitative systematic review following the ENTREQ (enhancing transparency in reporting the synthesis of qualitative research) framework. A search was made in MEDLINE/Pubmed and MeSH Database using the terms “precocious puberty” AND “brain tumor” OR “posterior fossa tumor” OR “cerebellar tumor” OR “infratentorial tumor”, identifying five cases of pediatric patients with infratentorial tumors and CPP and a case of cerebellar ganglioglioma without hypothalamic−pituitary−gonadal axis involvement and/or intracranial hypertension. Our work highlights the importance of a multidisciplinary approach and extensive central nervous system imaging for patients presenting with CPP in order to detect possible tumor association. Moreover, we believe that this manuscript could contribute to stimulate other research because the exact mechanism of CPP in infratentorial brain lesions has not been understood yet. |
format | Online Article Text |
id | pubmed-8544465 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-85444652021-10-26 A Rare Case of Posterior Fossa Tumor and Central Precocious Puberty: Case Presentation and Review of the Literature Rana, Roberta Perrillo, Teresa Santoro, Nicola Ortolani, Federica Messina, Raffaella Resta, Mariachiara Perrucci, Ilenia Ingravallo, Giuseppe Cazzato, Gerardo Grassi, Massimo Pesce, Sabino Signorelli, Francesco Neurol Int Case Report Central precocious puberty (CPP) is a condition that causes early gonadotropin-dependent sexual development; CPP is idiopathic in girls in most cases, whereas more than 50% of boys have an identifiable etiology. We conducted a qualitative systematic review following the ENTREQ (enhancing transparency in reporting the synthesis of qualitative research) framework. A search was made in MEDLINE/Pubmed and MeSH Database using the terms “precocious puberty” AND “brain tumor” OR “posterior fossa tumor” OR “cerebellar tumor” OR “infratentorial tumor”, identifying five cases of pediatric patients with infratentorial tumors and CPP and a case of cerebellar ganglioglioma without hypothalamic−pituitary−gonadal axis involvement and/or intracranial hypertension. Our work highlights the importance of a multidisciplinary approach and extensive central nervous system imaging for patients presenting with CPP in order to detect possible tumor association. Moreover, we believe that this manuscript could contribute to stimulate other research because the exact mechanism of CPP in infratentorial brain lesions has not been understood yet. MDPI 2021-10-20 /pmc/articles/PMC8544465/ /pubmed/34698255 http://dx.doi.org/10.3390/neurolint13040053 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Rana, Roberta Perrillo, Teresa Santoro, Nicola Ortolani, Federica Messina, Raffaella Resta, Mariachiara Perrucci, Ilenia Ingravallo, Giuseppe Cazzato, Gerardo Grassi, Massimo Pesce, Sabino Signorelli, Francesco A Rare Case of Posterior Fossa Tumor and Central Precocious Puberty: Case Presentation and Review of the Literature |
title | A Rare Case of Posterior Fossa Tumor and Central Precocious Puberty: Case Presentation and Review of the Literature |
title_full | A Rare Case of Posterior Fossa Tumor and Central Precocious Puberty: Case Presentation and Review of the Literature |
title_fullStr | A Rare Case of Posterior Fossa Tumor and Central Precocious Puberty: Case Presentation and Review of the Literature |
title_full_unstemmed | A Rare Case of Posterior Fossa Tumor and Central Precocious Puberty: Case Presentation and Review of the Literature |
title_short | A Rare Case of Posterior Fossa Tumor and Central Precocious Puberty: Case Presentation and Review of the Literature |
title_sort | rare case of posterior fossa tumor and central precocious puberty: case presentation and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544465/ https://www.ncbi.nlm.nih.gov/pubmed/34698255 http://dx.doi.org/10.3390/neurolint13040053 |
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