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Loss of the Extracellular Matrix Protein DIG-1 Causes Glial Fragmentation, Dendrite Breakage, and Dendrite Extension Defects

The extracellular matrix (ECM) guides and constrains the shape of the nervous system. In C. elegans, DIG-1 is a giant ECM component that is required for fasciculation of sensory dendrites during development and for maintenance of axon positions throughout life. We identified four novel alleles of di...

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Detalles Bibliográficos
Autores principales: Chong, Megan K., Cebul, Elizabeth R., Mizeracka, Karolina, Heiman, Maxwell G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544517/
https://www.ncbi.nlm.nih.gov/pubmed/34698211
http://dx.doi.org/10.3390/jdb9040042