Novel Binding Partners for CCT and PhLP1 Suggest a Common Folding Mechanism for WD40 Proteins with a 7-Bladed Beta-Propeller Structure

This study investigates whether selected WD40 proteins with a 7-bladed β-propeller structure, similar to that of the β subunit of the G protein heterotrimer, interact with the cytosolic chaperonin CCT and its known binding partner, PhLP1. Previous studies have shown that CCT is required for the fold...

Descripción completa

Detalles Bibliográficos
Autores principales: Mak, Wai Shun, Tsang, Tsz Ming, Chan, Tsz Yin, Lukov, Georgi L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544692/
https://www.ncbi.nlm.nih.gov/pubmed/34698247
http://dx.doi.org/10.3390/proteomes9040040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544692/
https://www.ncbi.nlm.nih.gov/pubmed/34698247
http://dx.doi.org/10.3390/proteomes9040040

Ejemplares similares