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The Prevalence of and Documented Indications for Antipsychotic Prescribing in Irish Nursing Homes

Background: Antipsychotic medications are often used ‘off-licence’ to treat neuropsychiatric symptoms and disorders of aging and to manage behavioural and psychological symptoms of dementia despite the warnings of adverse effects. Objective: To establish the prevalence of and documented indication f...

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Autores principales: Kelleher, Jayne E., Weedle, Peter, Donovan, Maria D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544697/
https://www.ncbi.nlm.nih.gov/pubmed/34698248
http://dx.doi.org/10.3390/pharmacy9040160
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author Kelleher, Jayne E.
Weedle, Peter
Donovan, Maria D.
author_facet Kelleher, Jayne E.
Weedle, Peter
Donovan, Maria D.
author_sort Kelleher, Jayne E.
collection PubMed
description Background: Antipsychotic medications are often used ‘off-licence’ to treat neuropsychiatric symptoms and disorders of aging and to manage behavioural and psychological symptoms of dementia despite the warnings of adverse effects. Objective: To establish the prevalence of and documented indication for antipsychotic medication use in the Irish nursing home setting. Setting: This study was conducted in six nursing homes located in Co. Cork, Ireland. Method: A retrospective, cross-sectional study was employed. All patients who met the inclusion criteria (≥65 years, residing in a nursing home on a long-term basis) were eligible for inclusion. There were 120 nursing home residents recruited to the study. Main Outcome Measure: The prevalence of antipsychotic medication use in nursing home residents (with and without dementia). Results: The overall prevalence of antipsychotic prescribing was found to be 48% and patients with dementia were significantly more likely to be prescribed an antipsychotic compared to those without dementia (67% vs. 25%) (χ(2) (1, N = 120) = 21.541, p < 0.001). In the cohort of patients with dementia, there was a trend approaching significance (p = 0.052) of decreasing antipsychotic use with increasing age (age 65–74 = 90%; age 75–84 = 71%; age 85 and over = 58%). An indication was documented for 84% of the antipsychotic prescriptions in this cohort. Conclusions: The findings of this study highlight that high rates of antipsychotic medication use remains an issue in Irish nursing homes. Further work should explore factors in influencing prescribing of these medications in such settings.
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spelling pubmed-85446972021-10-26 The Prevalence of and Documented Indications for Antipsychotic Prescribing in Irish Nursing Homes Kelleher, Jayne E. Weedle, Peter Donovan, Maria D. Pharmacy (Basel) Article Background: Antipsychotic medications are often used ‘off-licence’ to treat neuropsychiatric symptoms and disorders of aging and to manage behavioural and psychological symptoms of dementia despite the warnings of adverse effects. Objective: To establish the prevalence of and documented indication for antipsychotic medication use in the Irish nursing home setting. Setting: This study was conducted in six nursing homes located in Co. Cork, Ireland. Method: A retrospective, cross-sectional study was employed. All patients who met the inclusion criteria (≥65 years, residing in a nursing home on a long-term basis) were eligible for inclusion. There were 120 nursing home residents recruited to the study. Main Outcome Measure: The prevalence of antipsychotic medication use in nursing home residents (with and without dementia). Results: The overall prevalence of antipsychotic prescribing was found to be 48% and patients with dementia were significantly more likely to be prescribed an antipsychotic compared to those without dementia (67% vs. 25%) (χ(2) (1, N = 120) = 21.541, p < 0.001). In the cohort of patients with dementia, there was a trend approaching significance (p = 0.052) of decreasing antipsychotic use with increasing age (age 65–74 = 90%; age 75–84 = 71%; age 85 and over = 58%). An indication was documented for 84% of the antipsychotic prescriptions in this cohort. Conclusions: The findings of this study highlight that high rates of antipsychotic medication use remains an issue in Irish nursing homes. Further work should explore factors in influencing prescribing of these medications in such settings. MDPI 2021-09-30 /pmc/articles/PMC8544697/ /pubmed/34698248 http://dx.doi.org/10.3390/pharmacy9040160 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kelleher, Jayne E.
Weedle, Peter
Donovan, Maria D.
The Prevalence of and Documented Indications for Antipsychotic Prescribing in Irish Nursing Homes
title The Prevalence of and Documented Indications for Antipsychotic Prescribing in Irish Nursing Homes
title_full The Prevalence of and Documented Indications for Antipsychotic Prescribing in Irish Nursing Homes
title_fullStr The Prevalence of and Documented Indications for Antipsychotic Prescribing in Irish Nursing Homes
title_full_unstemmed The Prevalence of and Documented Indications for Antipsychotic Prescribing in Irish Nursing Homes
title_short The Prevalence of and Documented Indications for Antipsychotic Prescribing in Irish Nursing Homes
title_sort prevalence of and documented indications for antipsychotic prescribing in irish nursing homes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544697/
https://www.ncbi.nlm.nih.gov/pubmed/34698248
http://dx.doi.org/10.3390/pharmacy9040160
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