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Fasting drives the metabolic, molecular, and geroprotective effects of a calorie restricted diet in mice
Calorie restriction (CR) promotes healthy aging in diverse species. Recently, it has been shown that fasting for a portion of each day has metabolic benefits and promotes lifespan. These findings complicate the interpretation of rodent CR studies, in which animals typically eat only once per day and...
Autores principales: | Pak, Heidi H., Haws, Spencer A., Green, Cara L., Koller, Mikaela, Lavarias, Mitchell T., Richardson, Nicole E., Yang, Shany E., Dumas, Sabrina N., Sonsalla, Michelle, Bray, Lindsey, Johnson, Michelle, Barnes, Stephen, Darley-Usmar, Victor, Zhang, Jianhua, Yen, Chi-Liang Eric, Denu, John M., Lamming, Dudley W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544824/ https://www.ncbi.nlm.nih.gov/pubmed/34663973 http://dx.doi.org/10.1038/s42255-021-00466-9 |
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