Cargando…

Modular assembly of dynamic models in systems biology

It is widely acknowledged that the construction of large-scale dynamic models in systems biology requires complex modelling problems to be broken up into more manageable pieces. To this end, both modelling and software frameworks are required to enable modular modelling. While there has been consist...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Michael, Gawthrop, Peter J., Cursons, Joseph, Crampin, Edmund J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544865/ https://www.ncbi.nlm.nih.gov/pubmed/34644304 http://dx.doi.org/10.1371/journal.pcbi.1009513

Ejemplares similares

Modular dynamic biomolecular modelling with bond graphs: the unification of stoichiometry, thermodynamics, kinetics and data
por: Gawthrop, Peter J., et al.
Publicado: (2021)

Systems analysis identifies miR-29b regulation of invasiveness in melanoma
por: Andrews, Miles C., et al.
Publicado: (2016)

Predicting expression: the complementary power of histone modification and transcription factor binding data
por: Budden, David M, et al.
Publicado: (2014)

High temporal resolution RNA-seq time course data reveals widespread synchronous activation between mammalian lncRNAs and neighboring protein-coding genes
por: Muskovic, Walter, et al.
Publicado: (2022)

Sensitivity analysis of biochemical systems using bond graphs
por: Gawthrop, Peter J., et al.
Publicado: (2023)

Energy-based advection modelling using bond graphs
por: Gawthrop, Peter J., et al.
Publicado: (2022)

ProMoT: modular modeling for systems biology
por: Mirschel, Sebastian, et al.
Publicado: (2009)

Regulation of ERK-MAPK signaling in human epidermis
por: Cursons, Joseph, et al.
Publicado: (2015)

Principles of dynamical modularity in biological regulatory networks
por: Deritei, Dávid, et al.
Publicado: (2016)

Understanding nano-engineered particle–cell interactions: biological insights from mathematical models
por: Johnston, Stuart T., et al.
Publicado: (2021)

Modular Microphysiological System for Modeling of Biologic Barrier Function
por: Ishahak, Matthew, et al.
Publicado: (2020)

Spatially transformed fluorescence image data for ERK-MAPK and selected proteins within human epidermis
por: Cursons, Joseph, et al.
Publicado: (2015)

A platform for modular assembly and feeding of micro-organoids on standard Petri dishes
por: Nebuloni, Federico, et al.
Publicado: (2023)

A Modular Cloning System for Standardized Assembly of Multigene Constructs
por: Weber, Ernst, et al.
Publicado: (2011)

A Reappraisal of How to Build Modular, Reusable Models of Biological Systems
por: Neal, Maxwell L., et al.
Publicado: (2014)

Modular assembly of proteins on nanoparticles
por: Ma, Wenwei, et al.
Publicado: (2018)

Information theoretic approaches for inference of biological networks from continuous-valued data
por: Budden, David M., et al.
Publicado: (2016)

Mutation Rules and the Evolution of Sparseness and Modularity in Biological Systems
por: Friedlander, Tamar, et al.
Publicado: (2013)

Modelling modal gating of ion channels with hierarchical Markov models
por: Siekmann, Ivo, et al.
Publicado: (2016)

Designed proteins assemble antibodies into modular nanocages
por: Divine, Robby, et al.
Publicado: (2020)

Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines
por: Cursons, Joseph, et al.
Publicado: (2015)

Modular assembly of yeast cytochrome oxidase
por: McStay, Gavin P., et al.
Publicado: (2013)

Modularity in Biological Networks
por: Alcalá-Corona, Sergio Antonio, et al.
Publicado: (2021)

HomeRun Vector Assembly System: A Flexible and Standardized Cloning System for Assembly of Multi-Modular DNA Constructs
por: Li, Ming V., et al.
Publicado: (2014)

Distributed gene expression modelling for exploring variability in epigenetic function
por: Budden, David M., et al.
Publicado: (2016)

A new dynamic in vitro modular capillaries-venules modular system: Cerebrovascular physiology in a box
por: Cucullo, Luca, et al.
Publicado: (2013)

Modular cell biology: retroactivity and insulation
por: Del Vecchio, Domitilla, et al.
Publicado: (2008)

Dynamical Modularity in Automata Models of Biochemical Networks
por: Parmer, Thomas, et al.
Publicado: (2023)

Developing modular-oriented simulation models using system dynamics libraries
por: Karl, Christian K, et al.
Publicado: (2016)

Copper-Catalyzed Modular Assembly of Polyheterocycles
por: Wang, Qian, et al.
Publicado: (2020)

Hierarchical semantic composition of biosimulation models using bond graphs
por: Shahidi, Niloofar, et al.
Publicado: (2021)

Evolution of Complex Modular Biological Networks
por: Hintze, Arend, et al.
Publicado: (2008)

RNA modularity for synthetic biology
por: Grabow, Wade, et al.
Publicado: (2013)

BioBits™ Explorer: A modular synthetic biology education kit
por: Huang, Ally, et al.
Publicado: (2018)

A Modular Workflow for Model Building, Analysis, and Parameter Estimation in Systems Biology and Neuroscience
por: Santos, João P. G., et al.
Publicado: (2021)

Application of modular response analysis to medium- to large-size biological systems
por: Mekedem, Meriem, et al.
Publicado: (2022)

Exploration of the optimal modularity in assembly line design
por: Modrak, Vladimir, et al.
Publicado: (2022)

Modularity of biological systems: a link between structure and function
por: Kadelka, Claus, et al.
Publicado: (2023)

An ensemble model to optimize modularity in dynamic bipartite networks
por: Chaudhary, Neelu, et al.
Publicado: (2022)

Correction: Mutation Rules and the Evolution of Sparseness and Modularity in Biological Systems
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_5bci127v24dgassg7n6401if8q