A Case of Hepatitis C-Related Decompensated Cirrhosis Observed by MRI Imaging Data During Treatment With Direct-Acting Antiviral Agents

Sofosbuvir/velpatasvir therapy can safely treat hepatitis C virus (HCV)-related decompensated cirrhosis and has been shown to improve liver function at an early stage. However, the pathophysiology of the liver during treatment remains unclear. In this case report, we analyzed hepatic morphology on m...

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Detalles Bibliográficos
Autores principales: Nakamura, Atsushi, Yoshimura, Tsubasa, Ichikawa, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Gastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544910/
https://www.ncbi.nlm.nih.gov/pubmed/34722009
http://dx.doi.org/10.7759/cureus.19001
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author Nakamura, Atsushi
Yoshimura, Tsubasa
Ichikawa, Takeshi
author_facet Nakamura, Atsushi
Yoshimura, Tsubasa
Ichikawa, Takeshi
author_sort Nakamura, Atsushi
collection PubMed
description Sofosbuvir/velpatasvir therapy can safely treat hepatitis C virus (HCV)-related decompensated cirrhosis and has been shown to improve liver function at an early stage. However, the pathophysiology of the liver during treatment remains unclear. In this case report, we analyzed hepatic morphology on magnetic resonance imaging during the treatment period and confirmed that liver function and malnutrition were greatly improved with the elimination of HCV, and that rapid hemodynamic changes were occurring in the liver.
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spelling pubmed-85449102021-10-28 A Case of Hepatitis C-Related Decompensated Cirrhosis Observed by MRI Imaging Data During Treatment With Direct-Acting Antiviral Agents Nakamura, Atsushi Yoshimura, Tsubasa Ichikawa, Takeshi Cureus Gastroenterology Sofosbuvir/velpatasvir therapy can safely treat hepatitis C virus (HCV)-related decompensated cirrhosis and has been shown to improve liver function at an early stage. However, the pathophysiology of the liver during treatment remains unclear. In this case report, we analyzed hepatic morphology on magnetic resonance imaging during the treatment period and confirmed that liver function and malnutrition were greatly improved with the elimination of HCV, and that rapid hemodynamic changes were occurring in the liver. Cureus 2021-10-24 /pmc/articles/PMC8544910/ /pubmed/34722009 http://dx.doi.org/10.7759/cureus.19001 Text en Copyright © 2021, Nakamura et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Nakamura, Atsushi
Yoshimura, Tsubasa
Ichikawa, Takeshi
A Case of Hepatitis C-Related Decompensated Cirrhosis Observed by MRI Imaging Data During Treatment With Direct-Acting Antiviral Agents
title A Case of Hepatitis C-Related Decompensated Cirrhosis Observed by MRI Imaging Data During Treatment With Direct-Acting Antiviral Agents
title_full A Case of Hepatitis C-Related Decompensated Cirrhosis Observed by MRI Imaging Data During Treatment With Direct-Acting Antiviral Agents
title_fullStr A Case of Hepatitis C-Related Decompensated Cirrhosis Observed by MRI Imaging Data During Treatment With Direct-Acting Antiviral Agents
title_full_unstemmed A Case of Hepatitis C-Related Decompensated Cirrhosis Observed by MRI Imaging Data During Treatment With Direct-Acting Antiviral Agents
title_short A Case of Hepatitis C-Related Decompensated Cirrhosis Observed by MRI Imaging Data During Treatment With Direct-Acting Antiviral Agents
title_sort case of hepatitis c-related decompensated cirrhosis observed by mri imaging data during treatment with direct-acting antiviral agents
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544910/
https://www.ncbi.nlm.nih.gov/pubmed/34722009
http://dx.doi.org/10.7759/cureus.19001
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