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Electrocardiographic Abnormalities in Patients With Spinal Cord Injury With Deranged Lipid Profile

Introduction Spinal cord injury (SCI) can lead to severe disability and neurogenic shock, arrhythmias, autonomic dysfunction, pressure ulcers, etc., of the autonomic nervous system. Therefore, in these patients, cardiovascular problems should be investigated frequently. This study was conducted to e...

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Autores principales: Syed, Muhammad Usman Shah, Khan, Zunaira, Zulfiqar, Arif, Basham, Maleeha Ali, Abdul Haseeb, Hafiz, Azizullah, Saad, Ismail, Hebatalla, Elbahnasawy, Mohammad, Nadeem, Zubia, Karimi, Sundas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544921/
https://www.ncbi.nlm.nih.gov/pubmed/34722039
http://dx.doi.org/10.7759/cureus.18246
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author Syed, Muhammad Usman Shah
Khan, Zunaira
Zulfiqar, Arif
Basham, Maleeha Ali
Abdul Haseeb, Hafiz
Azizullah, Saad
Ismail, Hebatalla
Elbahnasawy, Mohammad
Nadeem, Zubia
Karimi, Sundas
author_facet Syed, Muhammad Usman Shah
Khan, Zunaira
Zulfiqar, Arif
Basham, Maleeha Ali
Abdul Haseeb, Hafiz
Azizullah, Saad
Ismail, Hebatalla
Elbahnasawy, Mohammad
Nadeem, Zubia
Karimi, Sundas
author_sort Syed, Muhammad Usman Shah
collection PubMed
description Introduction Spinal cord injury (SCI) can lead to severe disability and neurogenic shock, arrhythmias, autonomic dysfunction, pressure ulcers, etc., of the autonomic nervous system. Therefore, in these patients, cardiovascular problems should be investigated frequently. This study was conducted to evaluate the electrocardiographic (ECG) abnormalities in patients with spinal cord injury having inappropriate lipid profiles and their relationship with each other. Materials and methods This cross-sectional study was held in the Internal Medicine Department of Mayo Hospital, Lahore, for a one-year duration from May 2020 to May 2021. It included 58 patients with spinal cord injury, 35 of whom had paraplegia, and 23 had tetraplegia. Fasting blood samples were taken for lipid profile analysis. Twelve-lead ECGs three times a day for one month were taken and analyzed in the context of previously available ECGs. Results Out of 58, the lipid profiles were found abnormal in 47 patients, 18 of whom had a normal ECG. The lipid profile was normal in 12, of which only one patient had ECG abnormalities. Cholesterol levels were found normal in 39 patients and deranged in 19 patients; low-density lipoproteins in nine patients, triglycerides in 18 patients, and high-density lipoprotein values in one patient were abnormal. Conclusions Sinus bradycardia was the most common ECG abnormality found in SCI patients with deranged lipid profiles. Further studies are needed in the future to validate the findings of this study.
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spelling pubmed-85449212021-10-28 Electrocardiographic Abnormalities in Patients With Spinal Cord Injury With Deranged Lipid Profile Syed, Muhammad Usman Shah Khan, Zunaira Zulfiqar, Arif Basham, Maleeha Ali Abdul Haseeb, Hafiz Azizullah, Saad Ismail, Hebatalla Elbahnasawy, Mohammad Nadeem, Zubia Karimi, Sundas Cureus Cardiology Introduction Spinal cord injury (SCI) can lead to severe disability and neurogenic shock, arrhythmias, autonomic dysfunction, pressure ulcers, etc., of the autonomic nervous system. Therefore, in these patients, cardiovascular problems should be investigated frequently. This study was conducted to evaluate the electrocardiographic (ECG) abnormalities in patients with spinal cord injury having inappropriate lipid profiles and their relationship with each other. Materials and methods This cross-sectional study was held in the Internal Medicine Department of Mayo Hospital, Lahore, for a one-year duration from May 2020 to May 2021. It included 58 patients with spinal cord injury, 35 of whom had paraplegia, and 23 had tetraplegia. Fasting blood samples were taken for lipid profile analysis. Twelve-lead ECGs three times a day for one month were taken and analyzed in the context of previously available ECGs. Results Out of 58, the lipid profiles were found abnormal in 47 patients, 18 of whom had a normal ECG. The lipid profile was normal in 12, of which only one patient had ECG abnormalities. Cholesterol levels were found normal in 39 patients and deranged in 19 patients; low-density lipoproteins in nine patients, triglycerides in 18 patients, and high-density lipoprotein values in one patient were abnormal. Conclusions Sinus bradycardia was the most common ECG abnormality found in SCI patients with deranged lipid profiles. Further studies are needed in the future to validate the findings of this study. Cureus 2021-09-24 /pmc/articles/PMC8544921/ /pubmed/34722039 http://dx.doi.org/10.7759/cureus.18246 Text en Copyright © 2021, Syed et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Syed, Muhammad Usman Shah
Khan, Zunaira
Zulfiqar, Arif
Basham, Maleeha Ali
Abdul Haseeb, Hafiz
Azizullah, Saad
Ismail, Hebatalla
Elbahnasawy, Mohammad
Nadeem, Zubia
Karimi, Sundas
Electrocardiographic Abnormalities in Patients With Spinal Cord Injury With Deranged Lipid Profile
title Electrocardiographic Abnormalities in Patients With Spinal Cord Injury With Deranged Lipid Profile
title_full Electrocardiographic Abnormalities in Patients With Spinal Cord Injury With Deranged Lipid Profile
title_fullStr Electrocardiographic Abnormalities in Patients With Spinal Cord Injury With Deranged Lipid Profile
title_full_unstemmed Electrocardiographic Abnormalities in Patients With Spinal Cord Injury With Deranged Lipid Profile
title_short Electrocardiographic Abnormalities in Patients With Spinal Cord Injury With Deranged Lipid Profile
title_sort electrocardiographic abnormalities in patients with spinal cord injury with deranged lipid profile
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544921/
https://www.ncbi.nlm.nih.gov/pubmed/34722039
http://dx.doi.org/10.7759/cureus.18246
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