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Correlation of SARS-CoV-2 Subgenomic RNA with Antigen Detection in Nasal Midturbinate Swab Specimens

Among symptomatic outpatients, subgenomic RNA of severe acute respiratory syndrome coronavirus 2 in nasal midturbinate swab specimens was concordant with antigen detection but remained detectable in 13 (82.1%) of 16 nasopharyngeal swab specimens from antigen-negative persons. Subgenomic RNA in midtu...

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Autores principales: Immergluck, Katherine, Gonzalez, Mark D., Frediani, Jennifer K., Levy, Joshua M., Figueroa, Janet, Wood, Anna, Rogers, Beverly B., O’Neal, Jared, Elias-Marcellin, Roger, Suessmith, Allie, Sullivan, Julie, Schinazi, Raymond F., Babiker, Ahmed, Piantadosi, Anne, Vos, Miriam B., Martin, Greg S., Lam, Wilbur A., Waggoner, Jesse J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544990/
https://www.ncbi.nlm.nih.gov/pubmed/34424838
http://dx.doi.org/10.3201/eid2711.211135
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author Immergluck, Katherine
Gonzalez, Mark D.
Frediani, Jennifer K.
Levy, Joshua M.
Figueroa, Janet
Wood, Anna
Rogers, Beverly B.
O’Neal, Jared
Elias-Marcellin, Roger
Suessmith, Allie
Sullivan, Julie
Schinazi, Raymond F.
Babiker, Ahmed
Piantadosi, Anne
Vos, Miriam B.
Martin, Greg S.
Lam, Wilbur A.
Waggoner, Jesse J.
author_facet Immergluck, Katherine
Gonzalez, Mark D.
Frediani, Jennifer K.
Levy, Joshua M.
Figueroa, Janet
Wood, Anna
Rogers, Beverly B.
O’Neal, Jared
Elias-Marcellin, Roger
Suessmith, Allie
Sullivan, Julie
Schinazi, Raymond F.
Babiker, Ahmed
Piantadosi, Anne
Vos, Miriam B.
Martin, Greg S.
Lam, Wilbur A.
Waggoner, Jesse J.
author_sort Immergluck, Katherine
collection PubMed
description Among symptomatic outpatients, subgenomic RNA of severe acute respiratory syndrome coronavirus 2 in nasal midturbinate swab specimens was concordant with antigen detection but remained detectable in 13 (82.1%) of 16 nasopharyngeal swab specimens from antigen-negative persons. Subgenomic RNA in midturbinate swab specimens might be useful for routine diagnostics to identify active virus replication.
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spelling pubmed-85449902021-11-06 Correlation of SARS-CoV-2 Subgenomic RNA with Antigen Detection in Nasal Midturbinate Swab Specimens Immergluck, Katherine Gonzalez, Mark D. Frediani, Jennifer K. Levy, Joshua M. Figueroa, Janet Wood, Anna Rogers, Beverly B. O’Neal, Jared Elias-Marcellin, Roger Suessmith, Allie Sullivan, Julie Schinazi, Raymond F. Babiker, Ahmed Piantadosi, Anne Vos, Miriam B. Martin, Greg S. Lam, Wilbur A. Waggoner, Jesse J. Emerg Infect Dis Dispatch Among symptomatic outpatients, subgenomic RNA of severe acute respiratory syndrome coronavirus 2 in nasal midturbinate swab specimens was concordant with antigen detection but remained detectable in 13 (82.1%) of 16 nasopharyngeal swab specimens from antigen-negative persons. Subgenomic RNA in midturbinate swab specimens might be useful for routine diagnostics to identify active virus replication. Centers for Disease Control and Prevention 2021-11 /pmc/articles/PMC8544990/ /pubmed/34424838 http://dx.doi.org/10.3201/eid2711.211135 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Immergluck, Katherine
Gonzalez, Mark D.
Frediani, Jennifer K.
Levy, Joshua M.
Figueroa, Janet
Wood, Anna
Rogers, Beverly B.
O’Neal, Jared
Elias-Marcellin, Roger
Suessmith, Allie
Sullivan, Julie
Schinazi, Raymond F.
Babiker, Ahmed
Piantadosi, Anne
Vos, Miriam B.
Martin, Greg S.
Lam, Wilbur A.
Waggoner, Jesse J.
Correlation of SARS-CoV-2 Subgenomic RNA with Antigen Detection in Nasal Midturbinate Swab Specimens
title Correlation of SARS-CoV-2 Subgenomic RNA with Antigen Detection in Nasal Midturbinate Swab Specimens
title_full Correlation of SARS-CoV-2 Subgenomic RNA with Antigen Detection in Nasal Midturbinate Swab Specimens
title_fullStr Correlation of SARS-CoV-2 Subgenomic RNA with Antigen Detection in Nasal Midturbinate Swab Specimens
title_full_unstemmed Correlation of SARS-CoV-2 Subgenomic RNA with Antigen Detection in Nasal Midturbinate Swab Specimens
title_short Correlation of SARS-CoV-2 Subgenomic RNA with Antigen Detection in Nasal Midturbinate Swab Specimens
title_sort correlation of sars-cov-2 subgenomic rna with antigen detection in nasal midturbinate swab specimens
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544990/
https://www.ncbi.nlm.nih.gov/pubmed/34424838
http://dx.doi.org/10.3201/eid2711.211135
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