Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination

We describe a fatal case of multisystem inflammatory syndrome in an adult with onset 22 days after a second dose of mRNA coronavirus disease vaccine. Serologic and clinical findings indicated severe acute respiratory syndrome coronavirus 2 infection occurred before vaccination. The immunopathology o...

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Autores principales: Grome, Heather N., Threlkeld, Michael, Threlkeld, Steve, Newman, Charles, Martines, Roosecelis Brasil, Reagan-Steiner, Sarah, Whitt, Michael A., Gomes-Solecki, Maria, Nair, Nisha, Fill, Mary-Margaret, Jones, Timothy F., Schaffner, William, Dunn, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544993/
https://www.ncbi.nlm.nih.gov/pubmed/34586059
http://dx.doi.org/10.3201/eid2711.211612
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author Grome, Heather N.
Threlkeld, Michael
Threlkeld, Steve
Newman, Charles
Martines, Roosecelis Brasil
Reagan-Steiner, Sarah
Whitt, Michael A.
Gomes-Solecki, Maria
Nair, Nisha
Fill, Mary-Margaret
Jones, Timothy F.
Schaffner, William
Dunn, John
author_facet Grome, Heather N.
Threlkeld, Michael
Threlkeld, Steve
Newman, Charles
Martines, Roosecelis Brasil
Reagan-Steiner, Sarah
Whitt, Michael A.
Gomes-Solecki, Maria
Nair, Nisha
Fill, Mary-Margaret
Jones, Timothy F.
Schaffner, William
Dunn, John
author_sort Grome, Heather N.
collection PubMed
description We describe a fatal case of multisystem inflammatory syndrome in an adult with onset 22 days after a second dose of mRNA coronavirus disease vaccine. Serologic and clinical findings indicated severe acute respiratory syndrome coronavirus 2 infection occurred before vaccination. The immunopathology of this syndrome, regardless of vaccination status, remains poorly understood.
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spelling pubmed-85449932021-11-06 Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination Grome, Heather N. Threlkeld, Michael Threlkeld, Steve Newman, Charles Martines, Roosecelis Brasil Reagan-Steiner, Sarah Whitt, Michael A. Gomes-Solecki, Maria Nair, Nisha Fill, Mary-Margaret Jones, Timothy F. Schaffner, William Dunn, John Emerg Infect Dis Dispatch We describe a fatal case of multisystem inflammatory syndrome in an adult with onset 22 days after a second dose of mRNA coronavirus disease vaccine. Serologic and clinical findings indicated severe acute respiratory syndrome coronavirus 2 infection occurred before vaccination. The immunopathology of this syndrome, regardless of vaccination status, remains poorly understood. Centers for Disease Control and Prevention 2021-11 /pmc/articles/PMC8544993/ /pubmed/34586059 http://dx.doi.org/10.3201/eid2711.211612 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Grome, Heather N.
Threlkeld, Michael
Threlkeld, Steve
Newman, Charles
Martines, Roosecelis Brasil
Reagan-Steiner, Sarah
Whitt, Michael A.
Gomes-Solecki, Maria
Nair, Nisha
Fill, Mary-Margaret
Jones, Timothy F.
Schaffner, William
Dunn, John
Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination
title Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination
title_full Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination
title_fullStr Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination
title_full_unstemmed Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination
title_short Fatal Multisystem Inflammatory Syndrome in Adult after SARS-CoV-2 Natural Infection and COVID-19 Vaccination
title_sort fatal multisystem inflammatory syndrome in adult after sars-cov-2 natural infection and covid-19 vaccination
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544993/
https://www.ncbi.nlm.nih.gov/pubmed/34586059
http://dx.doi.org/10.3201/eid2711.211612
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