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Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016–2017

We reconstructed the 2016–2017 Zika virus epidemic in Puerto Rico by using complete genomes to uncover the epidemic’s origin, spread, and evolutionary dynamics. Our study revealed that the epidemic was propelled by multiple introductions that spread across the island, intricate evolutionary patterns...

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Autores principales: Santiago, Gilberto A., Kalinich, Chaney C., Cruz-López, Fabiola, González, Glenda L., Flores, Betzabel, Hentoff, Aaron, Charriez, Keyla N., Fauver, Joseph R., Adams, Laura E., Sharp, Tyler M., Black, Allison, Bedford, Trevor, Ellis, Esther, Ellis, Brett, Waterman, Steve H., Paz-Bailey, Gabriela, Grubaugh, Nathan D., Muñoz-Jordán, Jorge L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544999/
https://www.ncbi.nlm.nih.gov/pubmed/34670646
http://dx.doi.org/10.3201/eid2711.211575
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author Santiago, Gilberto A.
Kalinich, Chaney C.
Cruz-López, Fabiola
González, Glenda L.
Flores, Betzabel
Hentoff, Aaron
Charriez, Keyla N.
Fauver, Joseph R.
Adams, Laura E.
Sharp, Tyler M.
Black, Allison
Bedford, Trevor
Ellis, Esther
Ellis, Brett
Waterman, Steve H.
Paz-Bailey, Gabriela
Grubaugh, Nathan D.
Muñoz-Jordán, Jorge L.
author_facet Santiago, Gilberto A.
Kalinich, Chaney C.
Cruz-López, Fabiola
González, Glenda L.
Flores, Betzabel
Hentoff, Aaron
Charriez, Keyla N.
Fauver, Joseph R.
Adams, Laura E.
Sharp, Tyler M.
Black, Allison
Bedford, Trevor
Ellis, Esther
Ellis, Brett
Waterman, Steve H.
Paz-Bailey, Gabriela
Grubaugh, Nathan D.
Muñoz-Jordán, Jorge L.
author_sort Santiago, Gilberto A.
collection PubMed
description We reconstructed the 2016–2017 Zika virus epidemic in Puerto Rico by using complete genomes to uncover the epidemic’s origin, spread, and evolutionary dynamics. Our study revealed that the epidemic was propelled by multiple introductions that spread across the island, intricate evolutionary patterns, and ≈10 months of cryptic transmission.
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spelling pubmed-85449992021-11-06 Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016–2017 Santiago, Gilberto A. Kalinich, Chaney C. Cruz-López, Fabiola González, Glenda L. Flores, Betzabel Hentoff, Aaron Charriez, Keyla N. Fauver, Joseph R. Adams, Laura E. Sharp, Tyler M. Black, Allison Bedford, Trevor Ellis, Esther Ellis, Brett Waterman, Steve H. Paz-Bailey, Gabriela Grubaugh, Nathan D. Muñoz-Jordán, Jorge L. Emerg Infect Dis Research Letter We reconstructed the 2016–2017 Zika virus epidemic in Puerto Rico by using complete genomes to uncover the epidemic’s origin, spread, and evolutionary dynamics. Our study revealed that the epidemic was propelled by multiple introductions that spread across the island, intricate evolutionary patterns, and ≈10 months of cryptic transmission. Centers for Disease Control and Prevention 2021-11 /pmc/articles/PMC8544999/ /pubmed/34670646 http://dx.doi.org/10.3201/eid2711.211575 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Santiago, Gilberto A.
Kalinich, Chaney C.
Cruz-López, Fabiola
González, Glenda L.
Flores, Betzabel
Hentoff, Aaron
Charriez, Keyla N.
Fauver, Joseph R.
Adams, Laura E.
Sharp, Tyler M.
Black, Allison
Bedford, Trevor
Ellis, Esther
Ellis, Brett
Waterman, Steve H.
Paz-Bailey, Gabriela
Grubaugh, Nathan D.
Muñoz-Jordán, Jorge L.
Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016–2017
title Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016–2017
title_full Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016–2017
title_fullStr Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016–2017
title_full_unstemmed Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016–2017
title_short Tracing the Origin, Spread, and Molecular Evolution of Zika Virus in Puerto Rico, 2016–2017
title_sort tracing the origin, spread, and molecular evolution of zika virus in puerto rico, 2016–2017
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8544999/
https://www.ncbi.nlm.nih.gov/pubmed/34670646
http://dx.doi.org/10.3201/eid2711.211575
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