Cargando…

Dynamical Evolution of COVID-19 in Italy With an Evaluation of the Size of the Asymptomatic Infective Population

The present work deals with an Ordinary Differential Equation (ODE) model specifically designed to describe the COVID-19 evolution in Italy. The model is particularised on the basis of National data about the infection status of the Italian population to obtain numerical solutions that effectively r...

Descripción completa

Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IEEE 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545173/
https://www.ncbi.nlm.nih.gov/pubmed/32750959
http://dx.doi.org/10.1109/JBHI.2020.3009038
_version_ 1784589962015932416
collection PubMed
description The present work deals with an Ordinary Differential Equation (ODE) model specifically designed to describe the COVID-19 evolution in Italy. The model is particularised on the basis of National data about the infection status of the Italian population to obtain numerical solutions that effectively reproduce the real data. Our epidemic model is a classical SEIR model that incorporates two compartments of infected subpopulations, representing diagnosed and undiagnosed individuals respectively, and an additional quarantine compartment. Possible control actions representing social, political, and medical interventions are also included. The numerical results of the proposed model identification by least square fitting are analysed and commented with special emphasis on the estimation of the number of asymptomatic infective individuals. Our fitting results are in good agreement with the epidemiological data. Short and long-term predictions on the evolution of the disease are also given.
format Online
Article
Text
id pubmed-8545173
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher IEEE
record_format MEDLINE/PubMed
spelling pubmed-85451732023-02-17 Dynamical Evolution of COVID-19 in Italy With an Evaluation of the Size of the Asymptomatic Infective Population IEEE J Biomed Health Inform Article The present work deals with an Ordinary Differential Equation (ODE) model specifically designed to describe the COVID-19 evolution in Italy. The model is particularised on the basis of National data about the infection status of the Italian population to obtain numerical solutions that effectively reproduce the real data. Our epidemic model is a classical SEIR model that incorporates two compartments of infected subpopulations, representing diagnosed and undiagnosed individuals respectively, and an additional quarantine compartment. Possible control actions representing social, political, and medical interventions are also included. The numerical results of the proposed model identification by least square fitting are analysed and commented with special emphasis on the estimation of the number of asymptomatic infective individuals. Our fitting results are in good agreement with the epidemiological data. Short and long-term predictions on the evolution of the disease are also given. IEEE 2020-07-14 /pmc/articles/PMC8545173/ /pubmed/32750959 http://dx.doi.org/10.1109/JBHI.2020.3009038 Text en © IEEE 2020. This article is free to access and download, along with rights for full text and data mining, re-use and analysis.
spellingShingle Article
Dynamical Evolution of COVID-19 in Italy With an Evaluation of the Size of the Asymptomatic Infective Population
title Dynamical Evolution of COVID-19 in Italy With an Evaluation of the Size of the Asymptomatic Infective Population
title_full Dynamical Evolution of COVID-19 in Italy With an Evaluation of the Size of the Asymptomatic Infective Population
title_fullStr Dynamical Evolution of COVID-19 in Italy With an Evaluation of the Size of the Asymptomatic Infective Population
title_full_unstemmed Dynamical Evolution of COVID-19 in Italy With an Evaluation of the Size of the Asymptomatic Infective Population
title_short Dynamical Evolution of COVID-19 in Italy With an Evaluation of the Size of the Asymptomatic Infective Population
title_sort dynamical evolution of covid-19 in italy with an evaluation of the size of the asymptomatic infective population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545173/
https://www.ncbi.nlm.nih.gov/pubmed/32750959
http://dx.doi.org/10.1109/JBHI.2020.3009038
work_keys_str_mv AT dynamicalevolutionofcovid19initalywithanevaluationofthesizeoftheasymptomaticinfectivepopulation
AT dynamicalevolutionofcovid19initalywithanevaluationofthesizeoftheasymptomaticinfectivepopulation
AT dynamicalevolutionofcovid19initalywithanevaluationofthesizeoftheasymptomaticinfectivepopulation
AT dynamicalevolutionofcovid19initalywithanevaluationofthesizeoftheasymptomaticinfectivepopulation