Cargando…

mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status

Mostrar otras versiones (1)

While mRNA vaccines are proving highly efficacious against SARS-CoV-2, it is important to determine how booster doses and prior infection influence the immune defense they elicit, and whether they protect against variants. Focusing on the T cell response, we conducted a longitudinal study of infecti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Neidleman, Jason, Luo, Xiaoyu, McGregor, Matthew, Xie, Guorui, Murray, Victoria, Greene, Warner C, Lee, Sulggi A, Roan, Nadia R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545397/ https://www.ncbi.nlm.nih.gov/pubmed/34636722 http://dx.doi.org/10.7554/eLife.72619

Ejemplares similares

mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status
por: Neidleman, Jason, et al.
Publicado: (2021)

Single-cell glycomics analysis by CyTOF-Lec reveals glycan features defining cells differentially susceptible to HIV
por: Ma, Tongcui, et al.
Publicado: (2022)

SARS-CoV-2-Specific T Cells Exhibit Phenotypic Features of Helper Function, Lack of Terminal Differentiation, and High Proliferation Potential
por: Neidleman, Jason, et al.
Publicado: (2020)

Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19
por: Neidleman, Jason, et al.
Publicado: (2021)

Subsets of Tissue CD4 T Cells Display Different Susceptibilities to HIV Infection and Death: Analysis by CyTOF and Single Cell RNA-seq
por: Luo, Xiaoyu, et al.
Publicado: (2022)

Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19
por: Neidleman, Jason, et al.
Publicado: (2021)

Protracted yet coordinated differentiation of long-lived SARS-CoV-2-specific CD8+ T cells during COVID-19 convalescence
por: Ma, Tongcui, et al.
Publicado: (2021)

Characterization of HIV-induced remodeling reveals differences in infection susceptibility of memory CD4(+) T cell subsets in vivo
por: Xie, Guorui, et al.
Publicado: (2021)

Human MAIT cells respond to and suppress HIV-1
por: Phetsouphanh, Chansavath, et al.
Publicado: (2021)

Deep Phenotypic Analysis of Blood and Lymphoid T and NK Cells From HIV+ Controllers and ART-Suppressed Individuals
por: George, Ashley F., et al.
Publicado: (2022)

Hyaluronic acid is a negative regulator of mucosal fibroblast-mediated enhancement of HIV infection
por: Egedal, Johanne H., et al.
Publicado: (2021)

Human thymopoiesis produces polyspecific CD8(+) α/β T cells responding to multiple viral antigens
por: Quiniou, Valentin, et al.
Publicado: (2023)

DNA methylation defines regional identity of human intestinal epithelial organoids and undergoes dynamic changes during development
por: Kraiczy, Judith, et al.
Publicado: (2019)

IgM and IgD B cell receptors differentially respond to endogenous antigens and control B cell fate
por: Noviski, Mark, et al.
Publicado: (2018)

Opposing effects of T cell receptor signal strength on CD4 T cells responding to acute versus chronic viral infection
por: Künzli, Marco, et al.
Publicado: (2021)

Female Genital Fibroblasts Diminish the In Vitro Efficacy of PrEP against HIV
por: George, Ashley F., et al.
Publicado: (2022)

Scrotal calciphylaxis in a fifty-one-year-old man with end-stage renal disease and prior bacteremia
por: Bahar, Piroz, et al.
Publicado: (2023)

SARS-CoV2 variant-specific replicating RNA vaccines protect from disease following challenge with heterologous variants of concern
por: Hawman, David W, et al.
Publicado: (2022)

The HIV-1 latent reservoir is largely sensitive to circulating T cells
por: Warren, Joanna A, et al.
Publicado: (2020)

Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection
por: Hsiao, Feng, et al.
Publicado: (2020)

Loss of GTPase activating protein neurofibromin stimulates paracrine cell communication via macropinocytosis
por: Ghoshal, Pushpankur, et al.
Publicado: (2019)

Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4(+) and CD8(+) T-lymphocytes
por: Moshfegh, C.M., et al.
Publicado: (2019)

Role of Inflammation in Coronary Epicardial and Microvascular Dysfunction
por: Godo, Shigeo, et al.
Publicado: (2021)

Anti-inflammatory Treatment and Cardiovascular Outcomes: Results of Clinical Trials
por: Lorenzatti, Alberto J
Publicado: (2021)

Atherosclerotic Cardiovascular Disease in Rheumatoid Arthritis: Impact of Inflammation and Antirheumatic Treatment
por: Kerola, Anne Mirjam, et al.
Publicado: (2021)

The Role of C-reactive Protein in Patient Risk Stratification and Treatment
por: Arroyo-Espliguero, Ramón, et al.
Publicado: (2021)

Inflammation and Cardiovascular Disease: The Future
por: Arnold, Natalie, et al.
Publicado: (2021)

Small bowel stomas are associated with higher risk of circulating food-specific-IgG than patients with organic gastrointestinal conditions and colostomies
por: Carson, Walker K, et al.
Publicado: (2022)

IRAK1-dependent Regnase-1-14-3-3 complex formation controls Regnase-1-mediated mRNA decay
por: Akaki, Kotaro, et al.
Publicado: (2021)

Immune dynamics in SARS-CoV-2 experienced immunosuppressed rheumatoid arthritis or multiple sclerosis patients vaccinated with mRNA-1273
por: Verstegen, Niels JM, et al.
Publicado: (2022)

The Achilles Heel of the Trojan Horse Model of HIV-1 trans-Infection
por: Cavrois, Marielle, et al.
Publicado: (2008)

MicroRNAs of the miR-17~92 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression
por: Zhang, Xiang, et al.
Publicado: (2020)

No detectable alloreactive transcriptional responses under standard sample preparation conditions during donor-multiplexed single-cell RNA sequencing of peripheral blood mononuclear cells
por: McGinnis, Christopher S., et al.
Publicado: (2021)

IL18 signaling promotes homing of mature Tregs into the thymus
por: Peligero-Cruz, Cristina, et al.
Publicado: (2020)

Atypical presentation of COVID-19: Chronic bilateral testicular pain with lower extremity peripheral polyneuropathy, case report
por: Salazar, Aníbal, et al.
Publicado: (2021)

Endothelial SIRPα signaling controls VE-cadherin endocytosis for thymic homing of progenitor cells
por: Ren, Boyang, et al.
Publicado: (2022)

Transrectal Ultrasound Guided Needle Aspiration of a Prostatic Abscess: Salvage Treatment After Failed Transurethral Resection
por: Flores, David M., et al.
Publicado: (2015)

Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin
por: Ross, Ewan A., et al.
Publicado: (2015)

In Vitro Derived Dendritic Cells trans-Infect CD4 T Cells Primarily with Surface-Bound HIV-1 Virions
por: Cavrois, Marielle, et al.
Publicado: (2007)

Tumor control via targeting PD-L1 with chimeric antigen receptor modified NK cells
por: Robbins, Yvette, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_s6n3egf2iuia6fnd3hemmr8er9