mRNA vaccine-induced T cells respond identically to SARS-CoV-2 variants of concern but differ in longevity and homing properties depending on prior infection status

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While mRNA vaccines are proving highly efficacious against SARS-CoV-2, it is important to determine how booster doses and prior infection influence the immune defense they elicit, and whether they protect against variants. Focusing on the T cell response, we conducted a longitudinal study of infecti...

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Detalles Bibliográficos
Autores principales: Neidleman, Jason, Luo, Xiaoyu, McGregor, Matthew, Xie, Guorui, Murray, Victoria, Greene, Warner C, Lee, Sulggi A, Roan, Nadia R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545397/
https://www.ncbi.nlm.nih.gov/pubmed/34636722
http://dx.doi.org/10.7554/eLife.72619
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