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Impaired mRNA splicing and proteostasis in preadipocytes in obesity-related metabolic disease

Preadipocytes are crucial for healthy adipose tissue expansion. Preadipocyte differentiation is altered in obese individuals, which has been proposed to contribute to obesity-associated metabolic disturbances. Here, we aimed at identifying the pathogenic processes underlying impaired adipocyte diffe...

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Detalles Bibliográficos
Autores principales: Sánchez-Ceinos, Julia, Guzmán-Ruiz, Rocío, Rangel-Zúñiga, Oriol Alberto, López-Alcalá, Jaime, Moreno-Caño, Elena, Del Río-Moreno, Mercedes, Romero-Cabrera, Juan Luis, Pérez-Martínez, Pablo, Maymo-Masip, Elsa, Vendrell, Joan, Fernández-Veledo, Sonia, Fernández-Real, José Manuel, Laurencikiene, Jurga, Rydén, Mikael, Membrives, Antonio, Luque, Raul M, López-Miranda, José, Malagón, María M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545398/
https://www.ncbi.nlm.nih.gov/pubmed/34545810
http://dx.doi.org/10.7554/eLife.65996