Increased expression of GABA(A) receptor subunits associated with tonic inhibition in patients with temporal lobe epilepsy

Epilepsy animal models indicate pronounced changes in the expression and rearrangement of GABA(A) receptor subunits in the hippocampus and in para-hippocampal areas, including widespread downregulation of the subunits α5 and δ, and upregulation of α4, subunits that mediate tonic inhibition of GABA....

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Detalles Bibliográficos
Autores principales: Sperk, Günther, Pirker, Susanne, Gasser, Elisabeth, Wieselthaler, Anna, Bukovac, Anneliese, Kuchukhidze, Giorgi, Maier, Hans, Drexel, Meinrad, Baumgartner, Christoph, Ortler, Marin, Czech, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545616/
https://www.ncbi.nlm.nih.gov/pubmed/34708207
http://dx.doi.org/10.1093/braincomms/fcab239

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