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Pparg signaling controls bladder cancer subtype and immune exclusion

Pparg, a nuclear receptor, is downregulated in basal subtype bladder cancers that tend to be muscle invasive and amplified in luminal subtype bladder cancers that tend to be non-muscle invasive. Bladder cancers derive from the urothelium, one of the most quiescent epithelia in the body, which is com...

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Detalles Bibliográficos
Autores principales: Tate, Tiffany, Xiang, Tina, Wobker, Sarah E., Zhou, Mi, Chen, Xiao, Kim, Hyunwoo, Batourina, Ekatherina, Lin, Chyuan-Sheng, Kim, William Y., Lu, Chao, Mckiernan, James M., Mendelsohn, Cathy Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545976/
https://www.ncbi.nlm.nih.gov/pubmed/34697317
http://dx.doi.org/10.1038/s41467-021-26421-6