Riluzole-induced apoptosis in osteosarcoma is mediated through Yes-associated protein upon phosphorylation by c-Abl Kinase

Our lab has previously demonstrated Riluzole to be an effective drug in inhibiting proliferation and inducing apoptosis in both human and mouse osteosarcoma. Yes-associated protein is a transcription co-activator, known to be involved in cell proliferation or apoptosis depending on its protein partn...

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Detalles Bibliográficos
Autores principales: Raghubir, Marian, Azeem, Syeda M., Hasnat, Rifat, Rahman, Chowdhury N., Wong, Linda, Yan, Salina, Huang, Yu Qi, Zhagui, Raquel, Blyufer, Angelina, Tariq, Iffat, Tam, Cassey, Lhamo, Sonam, Cecilio, Lucas, Chowdhury, Yesmin, ChandThakuri, Shraddha, Mahajan, Shahana S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546089/
https://www.ncbi.nlm.nih.gov/pubmed/34697383
http://dx.doi.org/10.1038/s41598-021-00439-8

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