Cargando…
Safety and Effectiveness of Cell Therapy in Neurodegenerative Diseases: Take-Home Messages From a Pilot Feasibility Phase I Study of Progressive Supranuclear Palsy
Mesenchymal stromal cells (MSCs) are multipotent cells with anti-inflammatory properties. Here we tested the safety of MSCs in patients with progressive supranuclear palsy (PSP; ClinicalTrials.gov: NCT01824121; Eudract No. 2011-004051-39). Seven patients were treated. To improve the safety, protocol...
Autores principales: | Giordano, Rosaria, Canesi, Margherita, Isalberti, Maurizio, Marfia, Giovanni, Campanella, Rolando, Vincenti, Daniele, Cereda, Viviana, Ranghetti, Alessandra, Palmisano, Chiara, Isaias, Ioannis Ugo, Benti, Riccardo, Marotta, Giorgio, Lazzari, Lorenza, Montemurro, Tiziana, Viganò, Mariele, Budelli, Silvia, Montelatici, Elisa, Lavazza, Cristiana, Rivera-Ordaz, Araceli, Pezzoli, Gianni |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546103/ https://www.ncbi.nlm.nih.gov/pubmed/34712113 http://dx.doi.org/10.3389/fnins.2021.723227 |
Ejemplares similares
-
Finding a new therapeutic approach for no-option Parkinsonisms: mesenchymal stromal cells for progressive supranuclear palsy
por: Canesi, Margherita, et al.
Publicado: (2016) -
Autologous mesenchymal stem cell therapy for progressive supranuclear palsy: translation into a phase I controlled, randomized clinical study
por: Giordano, Rosaria, et al.
Publicado: (2014) -
How we make cell therapy in Italy
por: Montemurro, Tiziana, et al.
Publicado: (2015) -
Microtubule defects in mesenchymal stromal cells distinguish patients with Progressive Supranuclear Palsy
por: Calogero, Alessandra Maria, et al.
Publicado: (2018) -
Tips and Tricks for Validation of Quality Control Analytical Methods in Good Manufacturing Practice Mesenchymal Stromal Cell Production
por: Viganò, Mariele, et al.
Publicado: (2018)