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Diminazen Aceturate Protects Pulmonary Ischemia-Reperfusion Injury via Inhibition of ADAM17-Mediated Angiotensin-Converting Enzyme 2 Shedding

Lung ischemia-reperfusion (IR) injury is induced by pulmonary artery occlusion and reperfusion. Lung IR injury commonly happens after weaning from extracorporeal circulation, lung transplantation, and pulmonary thromboendarterectomy; it is a lethal perioperative complication. A definite therapeutic...

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Detalles Bibliográficos
Autores principales: Wang, Li-Fang, Sun, Yang-Yang, Pan, Qian, Yin, Yi-Qing, Tian, Xiao-Ming, Liu, Yue, Bu, Tegeleqi, Zhang, Qingy, Wang, Yong-An, Zhao, Jing, Luo, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546118/
https://www.ncbi.nlm.nih.gov/pubmed/34712133
http://dx.doi.org/10.3389/fphar.2021.713632

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