Bone marrow derived stromal cells from myelodysplastic syndromes are altered but not clonally mutated in vivo

The bone marrow (BM) stroma in myeloid neoplasms is altered and it is hypothesized that this cell compartment may also harbor clonal somatically acquired mutations. By exome sequencing of in vitro expanded mesenchymal stromal cells (MSCs) from n = 98 patients with myelodysplastic syndrome (MDS) and...

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Detalles Bibliográficos
Autores principales: Jann, Johann-Christoph, Mossner, Maximilian, Riabov, Vladimir, Altrock, Eva, Schmitt, Nanni, Flach, Johanna, Xu, Qingyu, Nowak, Verena, Obländer, Julia, Palme, Iris, Weimer, Nadine, Streuer, Alexander, Jawhar, Ahmed, Darwich, Ali, Jawhar, Mohammad, Metzgeroth, Georgia, Nolte, Florian, Hofmann, Wolf-Karsten, Nowak, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546146/
https://www.ncbi.nlm.nih.gov/pubmed/34697318
http://dx.doi.org/10.1038/s41467-021-26424-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546146/
https://www.ncbi.nlm.nih.gov/pubmed/34697318
http://dx.doi.org/10.1038/s41467-021-26424-3

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