Cargando…

Biophysical Evaluation of Rhesus Macaque Fc Gamma Receptors Reveals Similar IgG Fc Glycoform Preferences to Human Receptors

Rhesus macaques are a common non-human primate model used in the evaluation of human monoclonal antibodies, molecules whose effector functions depend on a conserved N-linked glycan in the Fc region. This carbohydrate is a target of glycoengineering efforts aimed at altering antibody effector functio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Crowley, Andrew R., Osei-Owusu, Nana Yaw, Dekkers, Gillian, Gao, Wenda, Wuhrer, Manfred, Magnani, Diogo M., Reimann, Keith A., Pincus, Seth H., Vidarsson, Gestur, Ackerman, Margaret E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546228/ https://www.ncbi.nlm.nih.gov/pubmed/34712242 http://dx.doi.org/10.3389/fimmu.2021.754710

Ejemplares similares

Affinity capillary electrophoresis – mass spectrometry permits direct binding assessment of IgG and FcγRIIa in a glycoform-resolved manner
por: Gstöttner, Christoph, et al.
Publicado: (2022)

Editorial: Roles of Fc Receptors in Disease and Therapy
por: Ganesan, Latha P., et al.
Publicado: (2020)

Biophysical and Functional Characterization of Rhesus Macaque IgG Subclasses
por: Boesch, Austin W., et al.
Publicado: (2016)

Multi-level glyco-engineering techniques to generate IgG with defined Fc-glycans
por: Dekkers, Gillian, et al.
Publicado: (2016)

Synthetic nanobodies as tools to distinguish IgG Fc glycoforms
por: Kao, Kevin S., et al.
Publicado: (2022)

Expression and function of FcγRII on NK cells in rhesus macaques
por: He, X, et al.
Publicado: (2012)

Site-Specific Glycosylation Mapping of Fc Gamma Receptor IIIb from Neutrophils of Individual Healthy Donors
por: Wojcik, Iwona, et al.
Publicado: (2020)

Glycoform-resolved FcɣRIIIa affinity chromatography–mass spectrometry
por: Lippold, Steffen, et al.
Publicado: (2019)

Evidence of variable human Fcγ receptor-Fc affinities across differentially-complexed IgG
por: Crowley, Andrew R., et al.
Publicado: (2023)

Comparison of the Fc glycosylation of fetal and maternal immunoglobulin G
por: Einarsdottir, Helga K., et al.
Publicado: (2012)

Fc gamma receptor IIIb binding of individual antibody proteoforms resolved by affinity chromatography–mass spectrometry
por: Lippold, Steffen, et al.
Publicado: (2021)

Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques
por: Tolbert, William D., et al.
Publicado: (2022)

MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N-Glycosylation
por: Sénard, Thomas, et al.
Publicado: (2020)

IgG-Fc glycosylation before and after rituximab treatment in immune thrombocytopenia
por: Schmidt, David E., et al.
Publicado: (2020)

Decoding the Human Immunoglobulin G-Glycan Repertoire Reveals a Spectrum of Fc-Receptor- and Complement-Mediated-Effector Activities
por: Dekkers, Gillian, et al.
Publicado: (2017)

EDIII-Fc induces protective immune responses against the Zika virus in mice and rhesus macaque
por: Su, Hailong, et al.
Publicado: (2023)

Transport of macrophage Fc receptors and Fc receptor-bound ligands to lysosomes
Publicado: (1986)

Fc Receptors and Fc Receptor-Like Molecules within the Immunoreceptor Family
por: Daëron, Marc
Publicado: (2016)

Afucosylated IgG Targets FcγRIV for Enhanced Tumor Therapy in Mice
por: Braster, Rens, et al.
Publicado: (2021)

Dataset from HDX-MS Studies of IgG1 Glycoforms and Their Interactions with the FcγRIa (CD64) Receptor
por: Anderson, Kyle W., et al.
Publicado: (2021)

Multivalent Fcγ-receptor engagement by a hexameric Fc-fusion protein triggers Fcγ-receptor internalisation and modulation of Fcγ-receptor functions
por: Qureshi, O. S., et al.
Publicado: (2017)

Cell targeting and immunostimulatory properties of a novel Fcγ-receptor-independent agonistic anti-CD40 antibody in rhesus macaques
por: Yan, Xianglei, et al.
Publicado: (2023)

The Neonatal Fc Receptor (FcRn): A Misnomer?
por: Pyzik, Michal, et al.
Publicado: (2019)

The neonatal Fc receptor in cancer FcRn in cancer
por: Cadena Castaneda, Diana, et al.
Publicado: (2020)

Human IgG3 with extended half-life does not improve Fc-gamma receptor-mediated cancer antibody therapies in mice
por: Braster, Rens, et al.
Publicado: (2017)

Patients with IgG1-anti-red blood cell autoantibodies show aberrant Fc-glycosylation
por: Sonneveld, Myrthe E., et al.
Publicado: (2017)

The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement
por: Brinkhaus, Maximilian, et al.
Publicado: (2022)

Fc-Glycosylation in Human IgG1 and IgG3 Is Similar for Both Total and Anti-Red-Blood Cell Anti-K Antibodies
por: Sonneveld, Myrthe E., et al.
Publicado: (2018)

FcγR Binding and ADCC Activity of Human IgG Allotypes
por: de Taeye, Steven W., et al.
Publicado: (2020)

Human IgE does not bind to human FcRn
por: Brinkhaus, Maximilian, et al.
Publicado: (2022)

Relative Quantitation of Subclass-Specific Murine IgG Fc N-Glycoforms by Multiple Reaction Monitoring
por: Han, Jing, et al.
Publicado: (2020)

Rational engineering of Fc/Fc receptor interactions to improve antibody potency
por: Doberstein, S, et al.
Publicado: (2003)

Fc Receptors as Adaptive Immunoreceptors
por: Daëron, Marc
Publicado: (2014)

Fc Receptors in Immune Responses
por: Mancardi, D., et al.
Publicado: (2014)

Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-19
por: Pongracz, Tamas, et al.
Publicado: (2022)

The Fc receptor on thymus-derived lymphocytes: II. Mitogen responsiveness of T lymphocytes bearing the Fc receptor
Publicado: (1975)

The influence of antibody engineering on Fc conformation and Fc receptor binding properties: Analysis of FcRn-binding engineered antibodies and an Fc fusion protein
por: Suzuki, Takuo, et al.
Publicado: (2021)

Characterization of the Rabbit Neonatal Fc Receptor (FcRn) and Analyzing the Immunophenotype of the Transgenic Rabbits That Overexpresses FcRn
por: Catunda Lemos, Ana Paula, et al.
Publicado: (2012)

Identity of the elusive IgM Fc receptor (FcμR) in humans
por: Kubagawa, Hiromi, et al.
Publicado: (2009)

Fcγ receptor binding is required for maximal immunostimulation by CD70-Fc
por: Dadas, Osman, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_srt7hiiqoq7o33fdp0rlv3t9f1